A study to investigate alternative regimens for pneumococcal vaccination of infants in a developing country
Grant number: 251648 | Funding period: 2003 - 2009
Streptococcus pneumoniae (Pnc) is the leading vaccine preventable cause of serious infection in infants. The current Pnc conjugate vaccine is very expensive (approximately USD $200-infant) so it is unlikely to be affordable for most developing countries. Moreover, as health care access in developing countries may be episodic and unreliable, many children do not receive either complete or timely vaccine courses. Therefore, it is important to investigate affordable and flexible ways to deliver this vaccine, which are safe and effective. A recent WHO-GAVI meeting to address impediments to the introduction of these vaccines in developing countries recognized the need to evaluate other regime..View full description
Related publications (4)
Impaired serotype-specific immune function following pneumococcal vaccination in infants with prior carriage
Paul V Licciardi, Fiona M Russell, Anne Balloch, Robert L Burton, Moon H Nahm, Gwendolyn Gilbert, Mimi LK Tang, Edward K Mulholland
The impact of prior nasopharyngeal carriage on serotype-specific IgG responses following immunization with pneumococcal conjugate ..
Pneumococcal polysaccharide vaccine at 12 months of age produces functional immune responses
Paul V Licciardi, Anne Balloch, Fiona M Russell, Robert L Burton, Jisheng Lin, Moon H Nahm, Edward K Mulholland, Mimi LK Tang
BACKGROUND: Infections with Streptococcus pneumoniae (pneumococcus) are a cause of significant child mortality. Pneumococcal glyco..
Antibodies to serotype 9V exhibit novel serogroup cross-reactivity following infant pneumococcal immunization
PV Licciardi, A Balloch, FM Russell, EK Mulholland, MLK Tang
Cross-reactivity within the pneumococcal immune response was examined in this study. Significant cross-reactivity between serotype..