Total Synthesis Of Novel Metabolites Form Microorganisms
Grant number: DP0449522
The main aim of this proposal is to achieve the chemical synthesis of a number of biologically active novel natural products isolated from microorganisms. This will involve the development of new methods as well as improvement on exisiting approaches developed so far. The targets will include the myxobacteria metabolites crocacins A, B and D and apicularen A, the streptomyces metabolites reveromycin A and spirofungin A and the fungal metabolite zaragozic acid C.