Molecular Epidemiology of Ovarian Research Institute

Grant number: OC000109

Abstract

PUBLIC ABSTRACT A major obstacle to preventive strategies for ovarian cancer is the lack of recognized modifiable risk factors. Age, a positive family history of ovarian cancer, having no children, lack of oral contraceptive use, and having intact uterine tubes are all known risk factors for ovarian cancer, but these are mostly not amenable to modification. One of the difficulties in studying risk factors for ovarian cancer is that it is one of the most complex human cancers, with several different subtypes of disease recognized. There are at least five types of the most common form of ovarian cancer (epithelial cancer), and each has quite distinct biologic features. There is evidence that p..

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