RISK FACTORS, SCREENING, PROPHYLAXIS AND OUTCOMES IN INDIVIDUALS FROM BREAST CANCER FAMILIES: KCONFAB FOLLOW-UP STUDY

Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC)

John L Hopper, Gillian S Dite, Robert J MacInnis, Yuyan Liao, Nur Zeinomar, Julia A Knight, Melissa C Southey, Roger L Milne, Wendy K Chung, Graham G Giles, Jeanine M Genkinger, Sue-Anne McLachlan, Michael L Friedlander, Antonis C Antoniou, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Saundra S Buys, Mary B Daly

2018-11-03

Body mass index and breast cancer survival: a Mendelian randomization analysis

Qi Guo, Stephen Burgess, Constance Turman, Manjeet K Bolla, Qin Wang, Michael Lush, Jean Abraham, Kristiina Aittomaki, Irene L Andrulis, Carmel Apicella, Volker Arndt, Myrto Barrdahl, Javier Benitez, Christine D Berg, Carl Blomqvist, Stig E Bojesen, Bernardo Bonanni, Judith S Brand, Hermann Brenner, Annegien Broeks

2017-12-01

Risk of uterine cancer for BRCA1 and BRCA2 mutation carriers

YC Lee, RL Milne, S Lheureux, M Friedlander, SA McLachlan, KL Martin, MQ Bernardini, C Smith, S Picken, S Nesci, JL Hopper, KA Phillips

2017-10-01

Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk

Xingyi Guo, Jirong Long, Chenjie Zeng, Kyriaki Michailidou, Maya Ghoussaini, Manjeet K Bolla, Qin Wang, Roger L Milne, Xiao-Ou Shu, Qiuyin Cai, Jonathan Beesley, Siddhartha P Kar, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, William Blot, Natalia Bogdanova

2015-11-01

Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast

Elinor Sawyer, Rebecca Roylance, Christos Petridis, Mark N Brook, Salpie Nowinski, Efterpi Papouli, Olivia Fletcher, Sarah Pinder, Andrew Hanby, Kelly Kohut, Patricia Gorman, Michele Caneppele, Julian Peto, Isabel dos Santos Silva, Nichola Johnson, Ruth Swann, Miriam Dwek, Katherine-Anne Perkins, Cheryl Gillett, Richard Houlston

2014-04-01

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

D Agarwal, S Pineda, K Michailidou, J Herranz, G Pita, LT Moreno, MR Alonso, J Dennis, Q Wang, MK Bolla, KB Meyer, P Menendez-Rodriguez, D Hardisson, M Mendiola, A Gonzalez-Neira, A Lindblom, S Margolin, A Swerdlow, A Ashworth, N Orr

2014-02-18

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Nichola Johnson, Frank Dudbridge, Nick Orr, Lorna Gibson, Michael E Jones, Minouk J Schoemaker, Elizabeth J Folkerd, Ben P Haynes, John L Hopper, Melissa C Southey, Gillian S Dite, Carmel Apicella, Marjanka K Schmidt, Annegien Broeks, Laura J Van't Veer, Femke Atsma, Kenneth Muir, Artitaya Lophatananon, Peter A Fasching, Matthias W Beckmann

2014-01-01

Diagnostic Chest X-Rays and Breast Cancer Risk before Age 50 Years for BRCA1 and BRCA2 Mutation Carriers

Esther M John, Valerie McGuire, Duncan Thomas, Robert Haile, Hilmi Ozcelik, Roger L Milne, Anna Felberg, Dee W West, Alexander Miron, Julia A Knight, Mary Beth Terry, Mary Daly, Saundra S Buys, Irene L Andrulis, John L Hopper, Melissa C Southey, Graham G Giles, Carmel Apicella, Heather Thorne, Alice S Whittemore

2013-09-01

Evidence of Gene-Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors

Stefan Nickels, Therese Truong, Rebecca Hein, Kristen Stevens, Katharina Buck, Sabine Behrens, Ursula Eilber, Martina Schmidt, Lothar Haeberle, Alina Vrieling, Mia Gaudet, Jonine Figueroa, Nils Schoof, Amanda B Spurdle, Anja Rudolph, Peter A Fasching, John L Hopper, Enes Makalic, Daniel F Schmidt, Melissa C Southey

2013-03-01

Psychosocial factors and uptake of risk-reducing salpingo-oophorectomy in women at high risk for ovarian cancer

Bettina Meiser, Melanie A Price, Phyllis N Butow, Janan Karatas, Judy Wilson, Louise Heiniger, Brandi Baylock, Margaret Charles, Sue-Anne McLachlan, Kelly-Anne Phillips

2013-03-01

High grade prostatic intraepithelial neoplasia does not display loss of heterozygosity at the mutation locus in BRCA2 mutation carriers with aggressive prostate cancer

Amber Willems-Jones, Liam Kavanagh, David Clouston, Damien Bolton, Stephen Fox, Heather Thorne

2012-12-01

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

Kristen N Stevens, Xianshu Wang, Zachary Fredericksen, Vernon S Pankratz, Mark H Greene, Irene L Andrulis, Mads Thomassen, Maria Caligo, Katherine L Nathanson, Anna Jakubowska, Ana Osorio, Ute Hamann, Andrew K Godwin, Dominique Stoppa-Lyonnet, Melissa Southey, Saundra S Buys, Christian F Singer, Thomas VO Hansen, Adalgeir Arason, Kenneth Offit

2012-11-01

9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium

Helen Warren, Frank Dudbridge, Olivia Fletcher, Nick Orr, Nichola Johnson, John L Hopper, Carmel Apicella, Melissa C Southey, Maryam Mahmoodi, Marjanka K Schmidt, Annegien Broeks, Sten Cornelissen, Linda M Braaf, Kenneth R Muir, Artitaya Lophatananon, Arkom Chaiwerawattana, Surapon Wiangnon, Peter A Fasching, Matthias W Beckmann, Arif B Ekici

2012-10-01

Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Rebecca Hein, Melanie Maranian, John L Hopper, Miroslaw K Kapuscinski, Melissa C Southey, Daniel J Park, Marjanka K Schmidt, Annegien Broeks, Frans BL Hogervorst, H Bas Bueno-de-Mesquit, Kenneth R Muir, Artitaya Lophatananon, Suthee Rattanamongkongul, Puttisak Puttawibul, Peter A Fasching, Alexander Hein, Arif B Ekici, Matthias W Beckmann, Olivia Fletcher, Nichola Johnson

2012-08-07

A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers

Yuan C Ding, Lesley McGuffog, Sue Healey, Eitan Friedman, Yael Laitman, null Shani-Paluch-Shimon, Bella Kaufman, Annelie Liljegren, Annika Lindblom, Hakan Olsson, Ulf Kristoffersson, Marie Stenmark-Askmalm, Beatrice Melin, Susan M Domchek, Katherine L Nathanson, Timothy R Rebbeck, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda

2012-08-01

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Diether Lambrechts, Therese Truong, Christina Justenhoven, Manjeet K Humphreys, Jean Wang, John L Hopper, Gillian S Dite, Carmel Apicella, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, Sten Cornelissen, Richard van Hien, Elinor Sawyer, Ian Tomlinson, Michael Kerin, Nicola Miller, Roger L Milne, M Pilar Zamora, Jose Ignacio Arias Perez

2012-07-01

Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers

Max Yan, Huiling Xu, Nic Waddell, Kristy Shield-Artin, Izhak Haviv, Michael J McKay, Stephen B Fox

2012-01-01

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

Christopher A Maxwell, Javier Benitez, Laia Gomez-Baldo, Ana Osorio, Nuria Bonifaci, Ricardo Fernandez-Ramires, Sylvain V Costes, Elisabet Guino, Helen Chen, Gareth JR Evans, Pooja Mohan, Isabel Catala, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo

2011-11-01

Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers

Jonathan Beesley, Hilda A Pickett, Sharon E Johnatty, Alison M Dunning, Xiaoqing Chen, Jun Li, Kyriaki Michailidou, Yi Lu, David N Rider, Rachel T Palmieri, Michael D Stutz, Diether Lambrechts, Evelyn Despierre, Sandrina Lambrechts, Ignace Vergote, Jenny Chang-Claude, Stefan Nickels, Alina Vrieling, Dieter Flesch-Janys, Shan Wang-Gohrke

2011-09-15

Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer

BE Kiely, ML Friedlander, RL Milne, L Stanhope, P Russell, MA Jenkins, P Weideman, SA McLachlan, P Grant, JL Hopper, KA Phillips

2011-09-01

Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2

Tu Nguyen-Dumont, Lars P Jordheim, Jocelyne Michelon, Nathalie Forey, Sandrine McKay-Chopin, Olga Sinilnikova, Florence Le Calvez-Kelm, Melissa C Southey, Sean V Tavtigian, Fabienne Lesueur

2011-05-11

Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2

A Osorio, RL Milne, R Alonso, G Pita, P Peterlongo, A Teule, KL Nathanson, SM Domchek, T Rebbeck, A Lasa, I Konstantopoulou, FB Hogervorst, S Verhoef, MF van Dooren, A Jager, MGEM Ausems, CM Aalfs, CJ van Asperen, M Vreeswijk, Q Waisfisz

2011-04-12

Nuclear and cytoplasmic expressions of ER beta 1 and ER beta 2 are predictive of response to therapy and alters prognosis in familial breast cancers

Max Yan, Mukta Rayoo, Elena A Takano, Stephen B Fox

2011-04-01

Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers

KA Schrader, S Masciari, N Boyd, C Salamanca, J Senz, DN Saunders, E Yorida, S Maines-Bandiera, P Kaurah, N Tung, ME Robson, PD Ryan, OI Olopade, SM Domchek, J Ford, C Isaacs, P Brown, J Balmana, AR Razzak, P Miron

2011-01-01

Subtypes of familial breast tumours revealed by expression and copy number profiling

Nic Waddell, Jeremy Arnold, Sibylle Cocciardi, Leonard da Silva, Anna Marsh, Joan Riley, Cameron N Johnstone, Mohammed Orloff, Guillaume Assie, Charis Eng, Lynne Reid, Patricia Keith, Max Yan, Stephen Fox, Peter Devilee, Andrew K Godwin, Frans BL Hogervorst, Fergus Couch, Sean Grimmond, James M Flanagan

2010-10-01

Association Between a Germline OCA2 Polymorphism at Chromosome 15q13.1 and Estrogen Receptor-Negative Breast Cancer Survival

Elizabeth M Azzato, Jonathan Tyrer, Peter A Fasching, Matthias W Beckmann, Arif B Ekici, Ruediger Schulz-Wendtland, Stig E Bojesen, Borge G Nordestgaard, Henrik Flyger, Roger L Milne, Jose Ignacio Arias, Primitiva Menendez, Javier Benitez, Jenny Chang-Claude, Rebecca Hein, Shan Wang-Gohrke, Heli Nevanlinna, Tuomas Heikkinen, Kristiina Aittomaki, Carl Blomqvist

2010-05-05

A BRCA1 promoter variant (rs11655505) and breast cancer risk

Paolo Verderio, Sara Pizzamiglio, Melissa C Southey, Amanda B Spurdle, John L Hopper, Xiaoqing Chen, Jonathan Beesley, Rita K Schmutzler, Christoph Engel, Barbara Burwinkel, Peter Bugert, Filomena Ficarazzi, Siranoush Manoukian, Monica Barile, Barbara Wappenschmidt, Georgia Chenevix-Trench, Paolo Radice, Paolo Peterlongo

2010-04-01

Use of DNA-Damaging Agents and RNA Pooling to Assess Expression Profiles Associated with BRCA1 and BRCA2 Mutation Status in Familial Breast Cancer Patients

Logan C Walker, Bryony A Thompson, Nic Waddell, Sean M Grimmond, Amanda B Spurdle

2010-02-01

A PALB2 mutation associated with high risk of breast cancer

Melissa C Southey, Zhi L Teo, James G Dowty, Fabrice A Odefrey, Daniel J Park, Marc Tischkowitz, Nelly Sabbaghian, Carmel Apicella, Graham B Byrnes, Ingrid Winship, Laura Baglietto, Graham G Giles, David E Goldgar, William D Foulkes, John L Hopper

2010-01-01

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

Jeremy M Arnold, David YH Choong, Ella R Thompson, Nic Waddell, Geoffrey J Lindeman, Jane E Visvader, Ian G Campbell, Georgia Chenevix-Trench

2010-01-01

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)

A Osorio, RL Milne, G Pita, P Peterlongo, T Heikkinen, J Simard, G Chenevix-Trench, AB Spurdle, J Beesley, X Chen, S Healey, SL Neuhausen, YC Ding, FJ Couch, X Wang, N Lindor, S Manoukian, M Barile, A Viel, L Tizzoni

2009-12-08

Rare, Evolutionarily Unlikely Missense Substitutions in ATM Confer Increased Risk of Breast Cancer

Sean V Tavtigian, Peter J Oefner, Davit Babikyan, Anne Hartmann, Sue Healey, Florence Le Calvez-Kelm, Fabienne Lesueur, Graham B Byrnes, Shu-Chun Chuang, Nathalie Forey, Corinna Feuchtinger, Lydie Gioia, Janet Hall, Mia Hashibe, Barbara Herte, Sandrine McKay-Chopin, Alun Thomas, Maxime P Vallee, Catherine Voegele, Penelope M Webb

2009-10-09

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

Sharon E Johnatty, Fergus J Couch, Zachary Fredericksen, Robert Tarrell, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Daphne Gschwantler-Kaulich, Christian F Singer, Christine Fuerhauser, Anneliese Fink-Retter, Susan M Domchek, Katherine L Nathanson, Vernon S Pankratz, Noralane M Lindor, Andrew K Godwin, Maria A Caligo, John Hopper, Melissa C Southey, Graham G Giles

2009-09-01

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

Antonis C Antoniou, Amanda B Spurdle, Olga M Sinilnikova, Sue Healey, Karen A Pooley, Rita K Schmutzler, Beatrix Versmold, Christoph Engel, Alfons Meindl, Norbert Arnold, Wera Hofmann, Christian Sutter, Dieter Niederacher, Helmut Deissler, Trinidad Caldes, Kati Kampjarvi, Heli Nevanlinna, Jacques Simard, Jonathan Beesley, Xiaoqing Chen

2008-04-01

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

Montserrat Garcia-Closas, Per Hall, Heli Nevanlinna, Karen Pooley, Jonathan Morrison, Douglas A Richesson, Stig E Bojesen, Borge G Nordestgaard, Christen K Axelsson, Jose I Arias, Roger L Milne, Gloria Ribas, Anna Gonzalez-Neira, Javier Benitez, Pilar Zamora, Hiltrud Brauch, Christina Justenhoven, Ute Hamann, Yon-Dschun Ko, Thomas Bruening

2008-04-01

Risk-reducing surgery, screening and chemoprevention practices of BRCA1 and BRCA2 mutation carriers: a prospective cohort study

K-A Phillips, MA Jenkins, GJ Lindeman, SA McLachlan, JM McKinley, PC Weideman, JL Hopper, ML Friedlander

2006-09-01