NHMRC Research Fellowship
Grant number: 350253
Related publications (9)
Alteration of the Thymic T Cell Repertoire by Rotavirus Infection Is Associated with Delayed Type 1 Diabetes Development in Non-Obese Diabetic Mice
Nicole L Webster, Christel Zufferey, Jessica A Pane, Barbara S Coulson
Rotaviruses are implicated as a viral trigger for the acceleration of type 1 diabetes in children. Infection of adult non-obese di..
Rotavirus acceleration of murine type 1 diabetes is associated with a T helper 1-dependent specific serum antibody response and virus effects in regional lymph nodes
JA Pane, NL Webster, KL Graham, G Holloway, C Zufferey, BS Coulson
AIMS/HYPOTHESIS: Rotavirus infection in at-risk children correlates with production of serum autoantibodies indicative of type 1 d..
Determinants of the Specificity of Rotavirus Interactions with the alpha 2 beta 1 Integrin
Fiona E Fleming, Kate L Graham, Yoshikazu Takada, Barbara S Coulson
The human α2β1 integrin binds collagen and acts as a cellular receptor for rotaviruses and human echovirus 1. These ligands requir..
Rotavirus Antagonizes Cellular Antiviral Responses by Inhibiting the Nuclear Accumulation of STAT1, STAT2, and NF-kappa B
Gavan Holloway, Thanhmai T Truong, Barbara S Coulson
A vital arm of the innate immune response to viral infection is the induction and subsequent antiviral effects of interferon (IFN)..
Rotavirus infection accelerates type 1 diabetes in mice with established insulitis
Kate L Graham, Natalie Sanders, Yan Tan, Janette Allison, Thomas WH Kay, Barbara S Coulson
Infection modulates type 1 diabetes, a common autoimmune disease characterized by the destruction of insulin-producing islet beta ..
Crystallization and preliminary X-ray diffraction analysis of the carbohydrate-recognizing domain (VP8*) of bovine rotavirus strain NCDV
Xing Yu, Annabel Guillon, Alex J Szyczew, Milton J Kiefel, Barbara S Coulson, Mark von Itzstein, Helen Blanchard
The infectivity of rotavirus is dramatically enhanced by proteolytic cleavage of its outer layer VP4 spike protein into two functi..
Rotavirus replication in intestinal cells differentially regulates integrin expression by a phosphatidylinositol 3-kinase-dependent pathway, resulting in increased cell adhesion and virus yield
Peter Halasz, Gavan Holloway, Stephen J Turner, Barbara S Coulson
Changes in the interactions between intestinal cells and their surrounding environment during virus infection have not been well d..
Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset
Kate L Graham, Joanne A O'Donnell, Yan Tan, Natalie Sanders, Emma M Carrington, Janette Allison, Barbara S Coulson
Rotaviruses have been implicated as a possible viral trigger for exacerbations in islet autoimmunity, suggesting they might modula..
Rotavirus activates JNK and p38 signaling pathways in intestinal cells, leading to AP-1-driven transcriptional responses and enhanced virus replication
Gavan Holloway, Barbara S Coulson
Rotavirus infection is known to regulate transcriptional changes in many cellular genes. The transcription factors NF-kappaB and A..