Chemical synthesis of bioactive metabolites and analogues from marine sources and myxobacteria
Grant number: DP0556064
This project could result in the production of a new type of anticancer compound. The proposal will study the synthesis of novel natural product analogues that could possess superior biological activities to the natural compounds. In addition, new chemistry may be developed which could be utilised to synthesise a number of related molecules.
Related publications (2)
Enantiospecific synthesis of the heparanase inhibitor ( )-trachyspic acid and stereoisomers from a common precursor
Steven C Zammit, Vito Ferro, Edward Hammond, Mark A Rizzacasa
The total synthesis of natural (+)-trachyspic acid and its enantiomer is described starting from a common 2-deoxy-d-ribose derivat..