PREFONTAL CORTICAL FUNCTION IN PEOPLE AT ULTRA-HIGH RISK FOR PSYCHOSIS: AN FRMI STUDY OF REFLEXIVE EYE MOVEMENTS

Has improved treatment contributed to the declining rate of transition to psychosis in ultra-high-risk cohorts?

MJC Formica, LJ Phillips, JA Hartmann, AR Yung, SJ Wood, A Lin, GP Amminger, PD McGorry, B Nelson

2020-05-10

BACKGROUND: The factors contributing to declining psychotic disorder transition rates in ultra-high-risk populations remain unclea..

Using clinical information to make individualized prognostic predictions in people at ultra high risk for psychosis

Andrea Mechelli, Ashleigh Lin, Stephen Wood, Patrick McGorry, Paul Amminger, Stefania Tognin, Philip McGuire, Jonathan Young, Barnaby Nelson, Alison Yung

2017-06-01

Recent studies have reported an association between psychopathology and subsequent clinical and functional outcomes in people at u..

Further examination of the reducing transition rate in ultra high risk for psychosis samples: The possible role of earlier intervention

B Nelson, HP Yuen, A Lin, SJ Wood, PD McGorry, JA Hartmann, AR Yung

2016-07-01

BACKGROUND: The rate of transition to psychotic disorder in ultra high risk (UHR) patients has declined in recent cohorts. The rea..

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

Vanessa L Cropley, Ashleigh Lin, Barnaby Nelson, Renate LEP Reniers, Alison R Yung, Cali F Bartholomeusz, Paul Klauser, Dennis Velakoulis, Patrick McGorry, Stephen J Wood, Christos Pantelis

2016-06-01

Declining transition rates to psychotic disorder in "ultra-high risk" clients: Investigation of a dilution effect

Jessica A Hartmann, Hok Pan Yuen, Patrick D McGorry, Alison R Yung, Ashleigh Lin, Stephen J Wood, Suzie Lavoie, Barnaby Nelson

2016-01-01

During recent years, a decrease has been noted in the rate of transition of ultra-high risk (UHR) clients to a psychotic disorder...

Demographic and clinical characteristics of young people seeking help at youth mental health services: baseline findings of the Transitions Study

Rosemary Purcell, Anthony F Jorm, Ian B Hickie, Alison R Yung, Christos Pantelis, G Paul Amminger, Nick Glozier, Eoin Killackey, Lisa J Phillips, Stephen J Wood, Susy Harrigan, Andrew Mackinnon, Elizabeth Scott, Daniel F Hermens, Adam J Guastella, Amanda Kenyon, Laura Mundy, Alissa Nichles, Antoinette Scaffidi, Daniela Spiliotacopoulos

2015-12-01

AIM: The Transitions Study was designed to establish a cohort of young people (12-25 years) seeking help for mental health problem..

Neighbourhood characteristics and the rate of identification of young people at ultra-high risk for psychosis

Brian O'Donoghue, Alison R Yung, Stephen Wood, Andrew Thompson, Ashleigh Lin, Patrick McGorry, Barnaby Nelson

2015-12-01

There is a higher incidence of psychotic disorders in more socially deprived neighbourhoods and a higher risk in migrants living i..

Investigation of orbitofrontal sulcogyral pattern in chronic schizophrenia

Vanessa L Cropley, Cali E Bartholomeusz, Peter Wu, Stephen J Wood, Tina Proffitt, Warrick J Brewer, Patricia M Desmond, Dennis Velakoulis, Christos Pantelis

2015-11-30

Abnormalities of orbitofrontal cortex (OFC) pattern type distribution have been associated with schizophrenia-spectrum disorders. ..

The relationship between stress, HPA axis functioning and brain structure in first episode psychosis over the first 12 weeks of treatment

Renate LEP Reniers, Belinda Garner, Christina Phassouliotis, Lisa J Phillips, Connie Markulev, Christos Pantelis, Sarah Bendall, Patrick D McGorry, Stephen J Wood

2015-02-28

Stress and abnormal hypothalamic-pituitary-adrenal axis functioning have been implicated in the early phase of psychosis and may p..

Divergent effects of first-generation and second-generation antipsychotics on cortical thickness in first-episode psychosis

BRE Ansell, DB Dwyer, SJ Wood, E Bora, WJ Brewer, TM Proffitt, D Velakoulis, PD McGorry, C Pantelis

2015-02-01

BACKGROUND: Whether there are differential effects of first-generation antipsychotics (FGAs) and second-generation antipsychotics ..

Social environmental risk factors for transition to psychosis in an ultra-high risk (UHR) population

Brian O'Donoghue, Barnaby Nelson, Hok Pan Yuen, Abbie Lane, Stephen Wood, Andrew Thompson, Ashleigh Lin, Patrick McGorry, Alison Yung

2014-11-01

OBJECTIVE: Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk fa..

Reduced parahippocampal cortical thickness in subjects at ultra-high risk for psychosis

S Tognin, A Riecher-Roessler, EM Meisenzahl, SJ Wood, C Hutton, SJ Borgwardt, N Koutsouleris, AR Yung, P Allen, LJ Phillips, PD McGorry, I Valli, D Velakoulis, B Nelson, J Woolley, C Pantelis, P McGuire, A Mechelli

2014-02-01

BACKGROUND: Grey matter volume and cortical thickness represent two complementary aspects of brain structure. Several studies have..

Long-term Follow-up of a Group at Ultra High Risk ("Prodromal") for Psychosis The PACE 400 Study

Barnaby Nelson, Hok Pan Yuen, Stephen J Wood, Ashleigh Lin, Daniela Spiliotacopoulos, Annie Bruxner, Christina Broussard, Magenta Simmons, Debra L Foley, Warrick J Brewer, Shona M Francey, G Paul Amminger, Andrew Thompson, Patrick D McGorry, Alison R Yung

2013-08-01

IMPORTANCE: The ultra high-risk (UHR) criteria were introduced to prospectively identify patients at high risk of psychotic disord..

Clinical Neuropsychology Within Adolescent and Young-Adult Psychiatry: Conceptualizing Theory and Practice

Kelly Allott, Tina-Marie Proffitt, Patrick D McGorry, Christos Pantelis, Stephen J Wood, Marnie Cumner, Warrick J Brewer

2013-01-01

Historically, clinical neuropsychology has made significant contributions to the understanding of brain-behavior relationships, pa..

Amygdala and insula volumes prior to illness onset in bipolar disorder: A magnetic resonance imaging study

Andreas Bechdolf, Stephen J Wood, Barnaby Nelson, Dennis Velakoulis, Murat Yuecel, Tsutomu Takahashi, Alison R Yung, Michael Berk, Michael T Wong, Christos Pantelis, Patrick D McGorry

2012-01-30

There are now numerous reports of neuroanatomical abnormalities in people with bipolar disorder. However, it remains unclear wheth..

Caudate nucleus volume in individuals at ultra-high risk of psychosis: A cross-sectional magnetic resonance imaging study

Katrina L Hannan, Stephen J Wood, Alison R Yung, Dennis Velakoulis, Lisa J Phillips, Bridget Soulsby, Gregor Berger, Patrick D McGorry, Christos Pantelis

2010-06-30

The aim of the present study was to investigate whether volumetric abnormalities of the caudate nuclei predate the onset of psycho..

Grey and white matter abnormalities are associated with impaired spatial working memory ability in first-episode schizophrenia

Luca Cocchi, Mark Walterfang, Renee Testa, Stephen J Wood, Marc L Seal, John Suckling, Tsutomu Takahashi, Tina-Marie Proffitt, Warrick J Brewer, Christopher Adamson, Bridget Soulsby, Dennis Velakoulis, Patrick D McGorry, Christos Pantelis

2009-12-01

Spatial working memory (SWM) dysfunction has been suggested as a trait marker of schizophrenia and implicates a diffuse network in..

Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study

D Sun, GW Stuart, M Jenkinson, SJ Wood, PD McGorry, D Velakoulis, TGM van Erp, PM Thompson, AW Toga, DJ Smith, TD Cannon, C Pantelis

2009-10-01

Schizophrenia is associated with structural brain abnormalities, but the timing of onset and course of these changes remains uncle..

Corpus callosum size and shape in first-episode affective and schizophrenia-spectrum psychosis

Mark Walterfang, Amanda G Wood, David C Reutens, Stephen J Wood, Jian Chen, Dennis Velakoulis, Patrick D McGorry, Christos Pantelis

2009-07-15

Reductions in the size of the anterior callosum have been described for both first-episode and established schizophrenia and bipol..

Attentional set-shifting ability in first-episode and established schizophrenia: Relationship to working memory

Christos Pantelis, Stephen J Wood, Tina M Proffitt, Renee Testa, Kate Mahony, Warrick J Brewer, Jo-Anne Buchanan, Dennis Velakoulis, Patrick D McGorry

2009-07-01

Patients with established schizophrenia perform poorly on attentional set-shifting tasks, due to a failure of inhibitory control a..

Diagnostic specificity of the insular cortex abnormalities in first-episode psychotic disorders

Tsutomu Takahashi, Stephen J Wood, Bridget Soulsby, Ryoichiro Tanino, Michael TH Wong, Patrick D McGorry, Michio Suzuki, Dennis Velakoulis, Christos Pantelis

2009-06-15

Volume reductions of the insular cortex have been described in schizophrenia, but it remains unclear whether other psychotic disor..

Progressive Gray Matter Reduction of the Superior Temporal Gyrus During Transition to Psychosis

Tsutomu Takahashi, Stephen J Wood, Alison R Yung, Bridget Soulsby, Patrick D McGorry, Michio Suzuki, Yasuhiro Kawasaki, Lisa J Phillips, Dennis Velakoulis, Christos Pantelis

2009-04-01

CONTEXT: Longitudinal magnetic resonance imaging studies have shown progressive gray matter reduction in the superior temporal gyr..

Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals

Daqiang Sun, Lisa Phillips, Dennis Velakoulis, Alison Yung, Patrick D McGorry, Stephen J Wood, Theo GM van Erp, Paul M Thompson, Arthur W Toga, Tyrone D Cannon, Christos Pantelis

2009-03-01

BACKGROUND: Schizophrenia and related psychoses are associated with brain structural abnormalities. Recent findings in 'at risk' p..

Adhesio interthalamica in individuals at high-risk for developing psychosis and patients with psychotic disorders

Tsutomu Takahashi, Murat Yucel, Alison R Yung, Stephen J Wood, Lisa J Phillips, Gregor E Berger, Anthony Ang, Bridget Soulsby, Patrick D McGorry, Michio Suzuki, Dennis Velakoulis, Christos Pantelis

2008-10-01

Abnormal neurodevelopment in midline structures such as the adhesio interthalamica (AI) has been reported in psychotic disorders, ..

Abnormal white matter microstructure in schizophrenia: A voxelwise analysis of axial and radial diffusivity

Marc L Seal, Murat Yuecel, Alex Fornito, Stephen J Wood, Ben J Harrison, Mark Walterfang, Gaby S Pell, Christos Pantelis

2008-04-01

Diffusion Tensor Imaging (DTI) investigations in schizophrenia have provided evidence of impairment in white matter as indicated b..

Fractionation of Verbal Memory Impairment in Schizophrenia and Schizophreniform Psychosis

Stephen J Wood, Aleks U Tarnawski, Tina M Proffitt, Warrick J Brewer, Greg R Savage, Vicki Anderson, Patrick D McGorry, Stephen J Wood, Aleks U Tarnawski, Tina M Proffitt, Warrick J Brewer, Greg R Savage, Vicki Anderson, Patrick D McGorry, Dennis Velakoulis, Christos Pantelis

2007-09-01

<jats:p> Objectives: The characterization, aetiology, and course of verbal memory deficits in schizophrenia remain ill defined. Th..