Characterising the Changes in Regulation of Visual Contrast Sensitivity in Glaucoma

Grant number: 353567 | Funding period: 2005 - 2008

Completed

Abstract

Glaucoma is the second leading cause of blindness in developed nations. A recent study estimated the number of Australian's that will need regular visual examination in 2030 either because they have glaucoma or glaucomatous risk factors to be at least 800,000. As the ultimate aim of glaucoma treatment is to maintain vision, visual functional assessment is of paramount importance to glaucoma management . The current standard measure for the assessment of visual loss due to glaucoma is visual field testing. Regrettably, substantial damage to retinal ganglion cells (the primary neurons affected by glaucoma) is often present prior to the discovery of visual field loss using standard measures. In..

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Related publications (6)

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Impairments of contrast discrimination and contrast adaptation in glaucoma

AM McKendrick, GP Sampson, MJ Walland, DR Badcock

2010-02-01

Purpose. Contrast detection is commonly measured clinically; however, discrimination between contrasts is also important for natur..

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Combining ganglion cell topology and data of patients with glaucoma to determine a structure-function map

A Turpin, GP Sampson, AM Mckendrick

2009-12-01

PURPOSE. To introduce techniques for deriving a map that relates visual field locations to optic nerve head (ONH) sectors and to u..

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Low spatial frequency contrast sensitivity deficits in migraine are not visual pathway selective

AM McKendrick, GP Sampson

2009-05-01

Some people who experience migraine demonstrate reduced visual contrast sensitivity that is measurable between migraines. Contrast..

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Spatial summation properties for magnocellular and parvocellular pathways in glaucoma

J Battista, DR Badcock, AM McKendrick

2009-03-01

PURPOSE. To examine the spatial summation properties for the magnocellular (M) and parvocellular (P) visual pathways in participan..

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Foveal contrast processing of increment and decrement targets is equivalently reduced in glaucoma

GP Sampson, DR Badcock, MJ Walland, AM McKendrick

2008-09-01

Background: Psychophysical measurement of the function of individual precortical visual pathways (magnocellular, parvocellular and..

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A two-stage neural spiking model of visual contrast detection in perimetry

SK Gardiner, WH Swanson, S Demirel, AM McKendrick, A Turpin, CA Johnson

2008-08-01

Perimetry is a commonly used clinical test for visual function, limited by high variability. The sources of this variability need ..

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