Slowing progression of knee osteoarthritis

Grant number: 454686 | Funding period: 2007 - 2009

Completed

Abstract

Knee arthritis is a painful, disabling, costly condition particularly affecting the elderly. As there is presently no cure for arthritis, interventions that slow progression of the disease will reduce the personal and societal burden of arthritis. Recently it has been postulated that specific exercise that targets how the muscles are controlled by the nervous system may have greater disease-modifying effects than exercise aimed at strengthening the muscles. Data are beginning to highlight the complexity of muscle strategies adopted by the nervous system to compensate for joint derangement in knee arthritis. It is our contention that there may be specific strategies that provide more optimal ..

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Related publications (6)

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Increased duration of co-contraction of medial knee muscles is associated with greater progression of knee osteoarthritis

Paul W Hodges, Wolbert van den Hoorn, Tim V Wrigley, Rana S Hinman, Kelly-Ann Bowles, Flavia M Cicuttini, Yuanyuan Wang, Kim Bennell

2016-02-01

BACKGROUND: As knee osteoarthritis (OA) cannot be cured, treatments that slow structural disease progression are a priority. Knee ..

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Sagittal plane joint loading is related to knee flexion in osteoarthritic gait

Mark W Creaby, Michael A Hunt, Rana S Hinman, Kim L Bennell

2013-10-01

BACKGROUND: High mechanical loading has been consistently linked with medial tibiofemoral osteoarthritis, and is considered to pla..

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Gait Differs Between Unilateral and Bilateral Knee Osteoarthritis

Mark W Creaby, Kim L Bennell, Michael A Hunt

2012-05-01

OBJECTIVES: To compare walking biomechanics in the most painful leg, and symmetry in biomechanics between legs, in individuals wit..

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Predicting dynamic knee joint load with clinical measures in people with medial knee osteoarthritis

Michael A Hunt, Kim L Bennell

2011-08-01

Knee joint loading, as measured by the knee adduction moment (KAM), has been implicated in the pathogenesis of knee osteoarthritis..

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Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial

KL Bennell, MA Hunt, TV Wrigley, DJ Hunter, FJ McManus, PW Hodges, L Li, RS Hinman

2010-05-01

OBJECTIVE: To determine whether hip abductor and adductor muscle strengthening reduces medial compartment knee load and improves s..

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The effects of hip muscle strengthening on knee load, pain, and function in people with knee osteoarthritis: a protocol for a randomised, single-blind controlled trial

Kim L Bennell, Michael A Hunt, Tim V Wrigley, David J Hunter, Rana S Hinman

2007-12-07

BACKGROUND: Lower limb strengthening exercises are an important component of the treatment for knee osteoarthritis (OA). Strengthe..

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