What Are The Breast Cancer Risks For An Australian Women Who Carries A Mutation In The Brca1 Or Brca2 Genes?

Grant number: 454696 | Funding period: 2007 - 2009

Completed

Abstract

About 10 years ago two genes, called BRCA1 and BRCA2, were discovered. The normal function of these genes is to prevent breast and other cancers from developing. All people have two copies of each gene, one inherited from their mother and one from their father. Women who have inherited a fault in one copy are at increased risk of breast and ovarian cancer. There has been considerable controversy about what their actual cancer risks are, especially about how those risks might depend on their age. We have already conducted studies on this and have developed the necessary statistical methods to address these issues by analysing data from the families in which there are faulty genes. In this stu..

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