2007 Program Grant - (Improving Stroke Outcomes: New Targets And Therapies)

Abstract

Previously we established a unique collaboration of researchers from the basic and clinical sciences.. The main aim of this ' vertically integrated ' model was to develop new therapies to improve stroke outcomes. We developed a system to identify ' off-the-shelf ' compounds which protect the brain after stroke onset. This involves data assimilation (meta-analysis) in a unique way, an approach which has attracted attention internationally. We are also completing an important clinical trial using the clot dissolving agent tPA to extend the time during which the drug may be effective beyond the three-hours currently used. In the next phase of our program we plan to expand the basic science comp..

Related publications (2)

An enriched environment increases activity in stroke patients undergoing rehabilitation in a mixed rehabilitation unit: a pilot non-randomized controlled trial

Heidi Janssen, Louise Ada, Julie Bernhardt, Patrick McElduff, Michael Pollack, Michael Nilsson, Neil J Spratt

2014-01-01

Stem cell-based therapy for experimental stroke: A systematic review and meta-analysis

Jennifer S Lees, Emily S Sena, Kieren J Egan, Ana Antonic, Simon A Koblar, David W Howells, Malcolm R Macleod

2012-10-01