Peptide Neurotransmission In Mental Health And Psychiatric Illness
Grant number: 509246 | Funding period: 2008 - 2010
Our laboratory recently discovered the brain 'transmitter' called 'relaxin-3', and are researching how it affects brain activity and animal physiology and behaviour. Findings suggest that relaxin-3 can modulate memory, responses to stress and other complex behaviours. Identifying the various actions of relaxin-3 in the brain could provide potential new treatments for conditions such as anxiety-depression, cognitive deficits (dementia) and schizophrenia.
Related publications (10)
Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice
Craig M Smith, Berenice E Chua, Cary Zhang, Andrew W Walker, Mouna Haidar, David Hawkes, Fazel Shabanpoor, Mohammad Akhter Hossain, John D Wade, K Johan Rosengren, Andrew L Gundlach