Inhibiting Tumour Cell Attachment In Breast Cancer Spread To Bone

Grant number: 509131 | Funding period: 2008 - 2010

Completed

Abstract

There are limited effective treatments for advanced breast cancer. The project investigates the role of a protein called integrin beta3 in the spread of breast tumours to bone, the most common site of secondary tumour formation (metastasis) in breast cancer patients. We will determine if the presence of integrin beta3 in breast tumours identifies patients at risk of developing bone metastases and test novel drugs against integrin beta3 in mice.