The link between depression and osteoporosis.
Grant number: 509103 | Funding period: 2008 - 2010
Both depression and osteoporosis are common, debilitating and expensive diseases and there is research to suggest that these conditions are related. This study will examine a potential common mechanism, inflammation, which may underlie both diseases. It will focus on circulating proteins which are associated with both depression and fragility fractures, and examine the role they play in both disorders.
Related publications (6)
Personality disorder is an excess risk factor for physical multimorbidity among women with mental state disorders
Shae E Quirk, Amanda L Stuart, Michael Berk, Julie A Pasco, Sharon L Brennan Olsen, Heli Koivumaa-Honkanen, Risto Honkanen, Pyry S Lukkala, Andrew M Chanen, Mark Kotowicz, Lana J Williams
We examined whether mental state disorders (lifetime mood, anxiety, eating, substance misuse) with comorbid personality disorder a..
The addition of depression to the Framingham Risk Equation model for predicting coronary heart disease risk in women
Adrienne O'Neil, Aaron J Fisher, Katherine J Kibbey, Felice N Jacka, Mark A Kotowicz, Lana J Williams, Amanda L Stuart, Michael Berk, Paul A Lewandowski, John J Atherton, Craig B Taylor, Julie A Pasco
BACKGROUND: Depression is widely considered to be an independent and robust predictor of Coronary Heart Disease (CHD), however is ..
Depression as a risk factor for fracture in women: A 10 year longitudinal study
Lana J Williams, Julie A Pasco, Henry Jackson, Litza Kiropoulos, Amanda L Stuart, Felice N Jacka, Michael Berk
BACKGROUND: Previous research has demonstrated deficits in bone mineral density (BMD) among individuals with depression. While red..
Excessive daytime sleepiness and falls among older men and women: cross-sectional examination of a population-based sample
Amie C Hayley, Lana J Williams, Gerard A Kennedy, Kara L Holloway, Michael Berk, Sharon L Brennan-Olsen, Julie A Pasco
BACKGROUND: Excessive daytime sleepiness (EDS) has been associated with an increased risk for falls among clinical samples of olde..
Psychiatric disorders, psychotropic medication use and falls among women: an observational study
Lana J Williams, Julie A Pasco, Amanda L Stuart, Felice N Jacka, Sharon L Brennan, Amelia G Dobbins, Risto Honkanen, Heli Koivumaa-Honkanen, Paivi H Rauma, Michael Berk
BACKGROUND: Psychotropic agents known to cause sedation are associated with an increased risk of falls, but the role of psychiatri..
Assessing oxidative pathway genes as risk factors for bipolar disorder
Janice M Fullerton, Yash Tiwari, Giti Agahi, Anna Heath, Michael Berk, Philip B Mitchell, Peter R Schofield
OBJECTIVES: There is a growing body of evidence implicating oxidative stress and the glutathione system in the pathogenesis of maj..