The link between depression and osteoporosis.

Grant number: 509103 | Funding period: 2008 - 2010

Completed

Abstract

Both depression and osteoporosis are common, debilitating and expensive diseases and there is research to suggest that these conditions are related. This study will examine a potential common mechanism, inflammation, which may underlie both diseases. It will focus on circulating proteins which are associated with both depression and fragility fractures, and examine the role they play in both disorders.

Related publications (6)

Scholarly works icon

Personality disorder is an excess risk factor for physical multimorbidity among women with mental state disorders

Shae E Quirk, Amanda L Stuart, Michael Berk, Julie A Pasco, Sharon L Brennan Olsen, Heli Koivumaa-Honkanen, Risto Honkanen, Pyry S Lukkala, Andrew M Chanen, Mark Kotowicz, Lana J Williams

2017-11-01

We examined whether mental state disorders (lifetime mood, anxiety, eating, substance misuse) with comorbid personality disorder a..

Scholarly works icon

The addition of depression to the Framingham Risk Equation model for predicting coronary heart disease risk in women

Adrienne O'Neil, Aaron J Fisher, Katherine J Kibbey, Felice N Jacka, Mark A Kotowicz, Lana J Williams, Amanda L Stuart, Michael Berk, Paul A Lewandowski, John J Atherton, Craig B Taylor, Julie A Pasco

2016-06-01

BACKGROUND: Depression is widely considered to be an independent and robust predictor of Coronary Heart Disease (CHD), however is ..

Scholarly works icon

Depression as a risk factor for fracture in women: A 10 year longitudinal study

Lana J Williams, Julie A Pasco, Henry Jackson, Litza Kiropoulos, Amanda L Stuart, Felice N Jacka, Michael Berk

2016-03-01

BACKGROUND: Previous research has demonstrated deficits in bone mineral density (BMD) among individuals with depression. While red..

Scholarly works icon

Excessive daytime sleepiness and falls among older men and women: cross-sectional examination of a population-based sample

Amie C Hayley, Lana J Williams, Gerard A Kennedy, Kara L Holloway, Michael Berk, Sharon L Brennan-Olsen, Julie A Pasco

2015-07-05

BACKGROUND: Excessive daytime sleepiness (EDS) has been associated with an increased risk for falls among clinical samples of olde..

Scholarly works icon

Psychiatric disorders, psychotropic medication use and falls among women: an observational study

Lana J Williams, Julie A Pasco, Amanda L Stuart, Felice N Jacka, Sharon L Brennan, Amelia G Dobbins, Risto Honkanen, Heli Koivumaa-Honkanen, Paivi H Rauma, Michael Berk

2015-04-08

BACKGROUND: Psychotropic agents known to cause sedation are associated with an increased risk of falls, but the role of psychiatri..

Scholarly works icon

Assessing oxidative pathway genes as risk factors for bipolar disorder

Janice M Fullerton, Yash Tiwari, Giti Agahi, Anna Heath, Michael Berk, Philip B Mitchell, Peter R Schofield

2010-08-01

OBJECTIVES: There is a growing body of evidence implicating oxidative stress and the glutathione system in the pathogenesis of maj..

University of Melbourne Researchers