How does infection with rotavirus alter the rate at which mice show diabetes?

Grant number: 509008 | Funding period: 2008 - 2010

Completed

Abstract

Rotavirus is the main cause of severe diarrhoea in children, and may contribute to progression to type 1 diabetes. We have now shown that rotavirus also modulates diabetes in mice, by a novel mechanism. In this project, the mechanism of this process will be elucidated and the capacity of human rotavirus to affect diabetes will be determined. This study will help determine the design of further human studies, and whether rotavirus vaccines also are possible modulators of diabetes development.

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University of Melbourne Researchers