Brain development during adolescence and the emergence of depression: A longitudinal MRI study.
Grant number: DP0878136 | Funding period: 2008 - 2012
Traditionally mental health services have focused on established disorders. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the inability to predict who is likely to go on to develop serious mental disorder. This study will provide critical information for understanding the risk processes that are operating during the critical phase of early adolescence, and will therefore make a fundamental contribution to our understanding of who, and what, to target in early intervention and prevention strategies.
Related publications (41)
Unraveling the Consequences of Childhood Maltreatment: Deviations From Typical Functional Neurodevelopment Mediate the Relationship Between Maltreatment History and Depressive Symptoms.
Divyangana Rakesh, Clare Kelly, Nandita Vijayakumar, Andrew Zalesky, Nicholas B Allen, Sarah Whittle
BACKGROUND: Childhood maltreatment is associated with lifelong psychiatric sequelae. However, our understanding of neurobiological..
Associations between early life stress and anterior pituitary gland volume development - A novel index of long-term hypothalamic-pituitary-adrenal axis functioning
Carmela Diaz-Arteche, Julian G Simmons, Despina E Ganella, Orli Schwartz, Jee Hyun Kim, Paige Farrow, Sarah Whittle
Previous research has established associations between early life stress (ELS) and altered pituitary gland volume (PGV) growth dur..
Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes
Megan M Herting, Cory Johnson, Kathryn L Mills, Nandita Vijayakumar, Meg Dennison, Chang Liu, Anne-Lise Goddings, Ronald E Dahl, Elizabeth R Sowell, Sarah Whittle, Nicholas B Allen, Christian K Tamnes
Linking the Serotonin Transporter Gene, Family Environments, Hippocampal Volume and Depression Onset: A Prospective Imaging Gene X Environment Analysis
Keriann Little, Craig A Olsson, George J Youssef, Sarah Whittle, Julian G Simmons, Murat Yuecel, Lisa B Sheeber, Debra L Foley, Nicholas B Allen
Sex-specific prediction of hypothalamic-pituitary-adrenal axis activity by pituitary volume during adolescence: A longitudinal study from 12 to 17 years of age
Michael Kaess, Julian G Simmons, Sarah Whittle, Martina Jovev, Andrew M Chanen, Murat Yuecel, Christos Pantelis, Nicholas B Allen