USING INTERGRATED FRONTIER AND SMART TECHNOLOGIES TO IDENTIFY NEW DRUG TARGETS FOR PARASITED CAUSEING MAJOR DISEASES IN HUMANS AND ANIMALS
Grant number: LX0882231 | Funding period: 2008 - 2009
The national/community benefits are (1) enhanced focus on animal and human health biotechnology through the development of anti-parasite compounds and/or vaccines; (2) improved and sustainable control of important parasites with decreased risk of induction of drug resistance; (3) increased profitability of agricultural animal production; (4) consolidation of a technology platform for further applications in genomics and post-genomics of pathogens of global significance and construction of a pipeline for the validation of drug targets; (5) capturing the benefits from fundamental research and strengthening links between fundamental and applied research; (6) increasing the quality and quantity ..View full description
Related publications (3)
Structural and functional characterisation of the fork head transcription factor-encoding gene, Hc-daf-16, from the parasitic nematode Haemonchus contortus (Strongylida)
Min Hu, James B Lok, Najju Ranjit, Holman C Massey, Paul W Sternberg, Robin B Gasser
Despite their phylogenetic diversity, parasitic nematodes share attributes of longevity and developmental arrest (=hypobiosis) wit..
Elucidating ANTS in worms using genomic and bioinformatic tools - Biotechnological prospects?
Min Hu, Weiwei Zhong, Bronwyn E Campbell, Paul W Sternberg, Mark W Pellegrino, Robin B Gasser
Adenine nucleotide translocators (ANTs) belong to the mitochondrial carrier family (MCF) of proteins. ATP production and consumpti..