CLINICAL - THE LINK BETWEEN BISPHOSPHONATE USE AND JAW OSTEONECROSIS

Grant number: 520172 | Funding period: 2008 - 2012

Completed

Abstract

Bisphosphonates are used in patients with bones that break easily due to conditions such as osteoporosis. Recent research suggests a possible association between these drugs and jaw bone breakdown called jaw osteonecrosis - a devastating condition with no current effective treatment. It is unclear why this condition affects only jaw bones. This study seeks to investigate if bacteria in the mouth, gum disease and saliva are involved in jaw osteonecrosis, which can then help to improve management.

Researchers