Clinical - Diffusion Mri to Assess Axonal Degeneration in Multiple Sclerosis

Abstract

Multiple Sclerosis (MS) involves inflammation and damage to nerve cells. New therapies are needed to minimize and reverse nerve cell damage. Currently, ways to judge the benefit of these therapies are primitive. We propose that assessing the benefits of these treatments in optic neuritis (inflammation of the eye nerve) is the way forward but first, we need to develop reliable tests to measure these treatments. This application proposes to use magnetic resonance imaging (MRI) for this purpose.

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