Peter Doherty Australian Biomedical Fellowship - Examination of the Involvement of Copper in the Development and Progression of Alzheimer's Disease

Abstract

Alzheimer’s disease (AD) is creating a growing burden upon Australian medical resources. Copper plays an important role in the development of AD and drugs designed to adjust brain copper levels are being tested for AD treatment and show therapeutic benefits. This project will determine how copper is involved in AD so that more effective drugs can be developed. Focus will primarily be on copper-binding proteins central to AD and establishing their role in AD development and progression.