RCT of Omega-3 Fatty Acids as Treatment of Subthreshold Symptoms in Young People at Ultra-High Risk for Psychosis

Grant number: 509388 | Funding period: 2008 - 2011

Completed

Abstract

Omega-3 fats are a type of polyunsaturated fat which has long been thought to be beneficial for health. The body cannot make its own omega-3 fats - they must be taken in through the diet, or in supplement form. Large population-based studies have suggested that a diet rich in omega-3 fats can reduce the risk of cardiovascular disease, lower blood pressure, cut the risk of cancers such as prostate and skin. The fats have also been touted as a treatment for arthritis, asthma, and inflamed bowels. A lack of omega-3s during foetal development can hinder brain and eye development. Other work has suggested that a diet rich in omega-3 may help improve mental health. Studies revealed beneficial effe..

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Related publications (3)

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The association of plasma inflammatory markers with omega-3 fatty acids and their mediating role in psychotic symptoms and functioning: An analysis of the NEURAPRO clinical trial

SR Susai, D Mongan, C Healy, M Cannon, B Nelson, C Markulev, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson

2022-01-01

Background: There is increasing evidence that dysregulation of polyunsaturated fatty acids (FAs) mediated membrane function plays ..

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The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis

GP Amminger, B Nelson, C Markulev, HP Yuen, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung, PD McGorry

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Background: NEURAPRO was a multicenter, placebo-controlled trial of long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) (fi..

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Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: The NEURAPRO randomized clinical trial

PD McGorry, B Nelson, C Markulev, HP Yuen, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung, G Paul Amminger

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IMPORTANCE :A promising treatment to prevent onset and improve outcomes in patients at ultrahigh risk for psychosis is dietary sup..