What increases the reactivity of airways in middle-age?
Grant number: 566931 | Funding period: 2009 - 2012
Increased airway reactivity (BHR) in middle-age increases the risk of chronic respiratory diseases (CRDs) in old age, which are recognised as a major public health problem. Knowledge on the causes of these conditions is currently limited. This project will improve our understanding of the childhood and adult causes of increased reactivity of the airways in middle-age. Such knowledge will help in identifying preventive strategies for middle age BHR and thereby CRDs in old age.
Related publications (4)
Is self-reported history of eczema and hay fever a valid measure of atopy in those who report current asthma?
Kathrine Pape, Vivi Schlunssen, Caroline Jane Lodge, Jennifer L Perret, E Haydn Walters, Dinh Bui, Bircan Erbas, Cecilie Svanes, Garun S Hamilton, Paul S Thomas, Karin S Hougaard, Michael J Abramson, Shyamali C Dharmage, Adrian J Lowe
Nocturnal symptoms perceived as asthma are associated with obstructive sleep apnoea risk, but not bronchial hyper-reactivity
Chamara V Senaratna, E Haydn Walters, Garun Hamilton, Adrian J Lowe, Caroline Lodge, John Burgess, Bircan Erbas, Graham G Giles, Paul Thomas, Michael J Abramson, Bruce Thompson, Jennifer L Perret, Shyamali C Dharmage
BACKGROUND AND OBJECTIVE: Obstructive sleep apnoea (OSA) and asthma are associated, and nocturnal breathing difficulty that is usu..
NOx in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults
Fahad M Aldakheel, Jane E Bourke, Paul S Thomas, Melanie C Matheson, Michael J Abramson, Garun S Hamilton, Caroline J Lodge, BruceR Thompson, E Haydn Walters, Katrina J Allen, Bircan Erbas, Jennifer L Perret, Shyamali C Dharmage, Adrian J Lowe
BACKGROUND: Asthma and allergic diseases are heterogeneous. Measurement of biomarkers in exhaled breath condensate (EBC) may help ..
Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort
John A Burgess, Melanie C Matheson, Fei Diao, David P Johns, Bircan Erbas, Adrian J Lowe, Lyle C Gurrin, Caroline J Lodge, Paul S Thomas, Stephen Morrison, Bruce R Thompson, Iain Feather, Jennifer L Perret, Michael J Abramson, Graham G Giles, John L Hopper, Shyamali C Dharmage, Eugene H Walters
The association between obesity and bronchial hyperresponsiveness (BHR) is incompletely characterised. Using the 2006 follow-up of..