Causes of human lymphatic and vascular malformations
Grant number: 566886 | Funding period: 2009 - 2012
Vascular malformations are abnormal growths of blood vessels that affect hundreds of children born in Australia every year. They range from small birthmarks to large destructive growths that cause chronic pain, bleeding and major deformity. This is the largest ever study to systematically look for the biological drivers that cause these growths so that drug treatments will ultimately be able to replace surgery as the first line treatment.
Related publications (1)
Isolation of human lymphatic malformation endothelial cells, their in vitro characterization and in vivo survival in a mouse xenograft model
Zerina Lokmic, Geraldine M Mitchell, Nicholas Koh Wee Chong, Jacqueline Bastiaanse, Yi-Wen Gerrand, Yiping Zeng, Elizabeth D Williams, Anthony J Penington