Psychiatric comorbidity in a model of epilepsy

Grant number: 566544 | Funding period: 2009 - 2011



People with epilepsy commonly suffer from severe mood disorders, such as depression and anxiety. These disturbances are underdiagnosed and undertreated, and are often more debilitating than the epilepsy. This project will investigate whether treatment of psychiatric disturbance with antidepressants also results in reduced seizure incidence in an animal model of epilepsy. Results generated from the study will provide clinicians strong rationale for aggressive treatment of such mood complaints.