Molecular imaging of brain tumours
Grant number: 566992 | Funding period: 2009 - 2012
The prognosis for malignant brain tumour patients that do not respond to intial treatment strategies is very poor. The fact that many of these patients patients will not survive longer than 12 months post diagnosis underscores the need to make treatment management decisions in a timely manner. This project seeks to develop and validate non-invasive early molecular imaging biomarkers that can quantify treatment efficacy months before traditional measures of efficacy are valid.
Related publications (4)
Probabilistic MRI Tractography of the Optic Radiation Using Constrained Spherical Deconvolution: A Feasibility Study
Jeremy C Lim, Pramit M Phal, Patricia M Desmond, Andrew D Nichols, Chris Kokkinos, Helen V Danesh-Meyer, Andrew H Kaye, Bradford A Moffat
BACKGROUND AND PURPOSE: Imaging the optic radiation (OR) is of considerable interest in studying diseases affecting the visual pat..
Nitroxide-Loaded Hexosomes Provide MRI Contrast in Vivo
Nicole Bye, Oliver E Hutt, Tracey M Hinton, Durga P Acharya, Lynne J Waddington, Bradford A Moffat, David K Wright, Hong X Wang, Xavier Mulet, Benjamin W Muir
The purpose of this work was to synthesize and screen, for their effectiveness to act as T1-enhancing magnetic resonance imaging (..
Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: A retrospective analysis
Ashray Gunjur, Eddie Lau, Yamna Taouk, Gail Ryan
INTRODUCTION: To evaluate the incidence and impact of early post-chemoradiation (cRT) 'pseudoprogression' (PsPD) amongst glioblast..