Inflammation & Neuronal Regulation Of Gastrointestinal Functions

Grant number: 566502 | Funding period: 2009 - 2011

Completed

Abstract

Gastrointestinal inflammation causes changes in neurons that control gut functions (motility and secretion). These changes in neuronal properties lead to the development of post-inflammatory motility disorders. This will be the first detailed study of neuronal ion channels that are changed after inflammation in the gut. Our study will open the way to the development of therapeutic agents to treat post-inflammatory IBS and other conditions that involve disorders of motility.