THE ROLE OF BHLH FACTORS IN NORMAL AND LEUKEMIC HAEMOPOIESIS

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

Sarah L Siggins, Nhu-Y N Nguyen, Matthew P McCormack, Sumitha Vasudevan, Rehan Villani, Stephen M Jane, Brandon J Wainwright, David J Curtis

2009-07-30

Hedgehog (Hh) ligands bind to the Patched1 (Ptch1) receptor, relieving repression of Smoothened, which leads to activation of the ..

Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival

George P Souroullas, Jessica M Salmon, Fred Sablitzky, David J Curtis, Margaret A Goodell

2009-02-06

Scl and Lyl1 encode two related basic-helix-loop-helix transcription factors implicated in T cell acute lymphoblastic leukemia. Pr..