Restoring hearing using stem cells
Grant number: 567117 | Funding period: 2009 - 2014
One in four Australians is predicted to experience some form of hearing loss by 2050. Hearing loss is irreversible and the chief clinical treatment available for severe to profound hearing loss is a cochlear implant. However, cochlear implant efficacy is limited by the degeneration of the auditory nerve following hearing loss. Using stem cells, this project will develop techniques to restore function to the auditory nerve through replacement of the specialised cells that comprise it.
Related publications (1)
Electrophysiological properties of neurosensory progenitors derived from human embryonic stem cells
Karina Needham, Tomoko Hyakumura, Niliksha Gunewardene, Mirella Dottori, Bryony A Nayagam
In severe cases of sensorineural hearing loss where the numbers of auditory neurons are significantly depleted, stem cell-derived ..