tRNA synthetases as drug targets in Plasmodium falciparum

Grant number: FT0990350 | Funding period: 2010 - 2013

Completed

Abstract

Malaria is a major worldwide infectious disease. The disease kills around 2 million people every year, and current drugs are increasingly failing due to parasite drug resistance, creating an urgent demand for new drugs, that inhibit different targets. The Fellow will study a new class of parasite drug targets, the transfer ribonucleic acid (tRNA) synthetase enzymes to find novel inhibitors. Compounds blocking these enzymes may lead to new drugs to combat malaria.

Related publications (18)

University of Melbourne Researchers