Sex hormones and social behaviour
Grant number: 628553 | Funding period: 2010 - 2012
Prevalence report by the Australian Advisory Board on Autism Spectrum Disorders (ASD) estimated that 1 child in every 160 children in the 6-12 year-old age group is affected by ASD. There is no cure for ASD and the causes are not understood. We propose that sex hormones may play a role in the development of these disorders. We will test this hypothesis using knockout and transgenic mouse models which have social interaction deficits and brain structure reminiscent of these disorders.
Related publications (5)
Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse
Michelle L Van Sinderen, Gregory R Steinberg, Sebastian B Jorgensen, Sarah Q To, Kevin C Knower, Colin D Clyne, Jane Honeyman, Jenny D Chow, Kerrie A Herridge, Margaret EE Jones, Evan R Simpson, Wah Chin Boon