The contribution of a protein present in normal cells to the spread of breast cancer

Grant number: 628729 | Funding period: 2010 - 2012

Completed

Abstract

Mortality in breast cancer rises to 80% in cases where secondary tumors form in other organs. To improve outcome, a better understanding of the processes involved in cancer spread is needed. Normal cells contribute to the growth and spread of a tumour and are a target for therapy. When a protein called caveolin-1 is lost from normal cells in a tumour, the prognosis for the patient is much worse. The aim of this project is to understand how this protein can regulate the spread of breast cancer.

University of Melbourne Researchers