Brain Tumors And Seizures
Grant number: 628301 | Funding period: 2010 - 2014
Seizures commonly develop in patients with brain tumours. Despite tumour resection, patients continue to experience seizures. Furthermore, patients can often be resistant to treatment with anti-epilepsy medications adding further burden to patient suffering, decreasing quality of life and overall survival. The cause is unknown and we propose identifiable causes are involved. This will provide effective targets for the development of medications for the treatment of these seizures.
Related publications (5)
Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging
Andrew Morokoff, Bradford A Moffat, Joel M Stein, Ravi Prakash Reddy Nanga, Patricia Desmond, Russell T Shinohara, Hari Hariharan, Rebecca Glarin, Katharine Drummond, Patrick Kwan, Ravinder Reddy, Terence J O'BRIEN, Kathryn A Davis
INTRODUCTION: Diffuse gliomas are incurable malignancies, which undergo inevitable progression and are associated with seizure in ..
IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low-grade gliomas
Simon V Liubinas, Giovanna M D'Abaco, Bradford M Moffat, Michael Gonzales, Frank Feleppa, Cameron J Nowell, Alexandra Gorelik, Katharine J Drummond, Terence J O'Brien, Andrew H Kaye, Andrew P Morokoff
Glutamate is associated with a higher risk of seizures in patients with gliomas
Tanya I Yuen, Andrew P Morokoff, Andrew Bjorksten, Giovanna D'Abaco, Lucy Paradiso, Sue Finch, Daniel Wong, Christopher A Reid, Kim L Powell, Kate J Drummond, Mark A Rosenthal, Andrew H Kaye, Terence J O'Brien