Interferon and neural injury
Grant number: 628391 | Funding period: 2010 - 2012
This project focuses on the role that inflammation plays in the progression of the type of neural injury seen in stroke victims. This project targets a specific pathway that is thought to be involved in the regulation of general inflammation but has not been greatly investigated in terms of the neural injury seen in stroke. Understanding the actions of this pathway may lead to future therapies that can be used to prime the brain to react in a positive way to stroke.
Related publications (3)
Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury
Ila P Karve, Moses Zhang, Mark Habgood, Tony Frugier, Kate M Brody, Maithili Sashindranath, C Joakim Ek, Stephane Chappaz, Ben T Kile, David Wright, Hong Wang, Leigh Johnston, Maria Daglas, Robert C Ates, Robert L Medcalf, Juliet M Taylor, Peter J Crack
Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes
Peter J Crack, Moses Zhang, Maria Cristina Morganti-Kossmann, Andrew J Morris, Jonathan M Wojciak, Jonathan K Fleming, Ila Karve, David Wright, Maithili Sashindranath, Yona Goldshmit, Alison Conquest, Maria Daglas, Leigh A Johnston, Robert L Medcalf, Roger A Sabbadini, Alice Pebay