Sympathetic Immune Crosstalk

Abstract

The two complex systems of the body, the immune system and the nervous system, communicate with each other. This proposal studies one of the major pathways from brain to immune system - sympathetic immuno-efferent nerves. In stroke, these pathways cause profound immunosuppression, causing susceptibility to infection. Their poorly understood central and peripheral pathways will be defined and mapped by this study.

Related publications (2)

The cholinergic anti-inflammatory pathway: A critical review

D Martelli, MJ McKinley, RM McAllen

2014-05-01

Neural regulation of inflammation: no neural connection from the vagus to splenic sympathetic neurons

BO Bratton, D Martelli, MJ McKinley, D Trevaks, CR Anderson, RM McAllen

2012-11-01