Porosity And Fracture Risk
Grant number: 628701 | Funding period: 2010 - 2012
We just discovered that bone lost with age occurs mostly from pores within the cortex (outer shell) of the bone; These pores become larger (porosity) making bones fragile. This process is poorly detected by bone density (currently used tool) so that most people with weak bones are missed. To address this issue, we have for the first time, develop a technology to accurately quantify porosity in living peoples. With teams around the world, we aim here to fill this gap in the diagnosis.
Related publications (4)
Cortical Porosity Identifies Women With Osteopenia at Increased Risk for Forearm Fractures
Yohann Bala, Roger Zebaze, Ali Ghasem-Zadeh, Elizabeth J Atkinson, Sandra Iuliano, James M Peterson, Shreyasee Amin, Ashild Bjornerem, L Joseph Melton, Helena Johansson, John A Kanis, Sundeep Khosla, Ego Seeman
New insights into the effects of primary hyperparathyroidism on the cortical and trabecular compartments of bone
Thuy DT Vu, Xiao Fang Wang, Qingju Wang, Natalie E Cusano, Dinaz Irani, Barbara C Silva, Ali Ghasem-Zadeh, Julia Udesky, Megan E Romano, Roger Zebaze, George Jerums, Stephanie Boutroy, John P Bilezikian, Ego Seeman