Young People With Old Knees: Knee Ligament Reconstruction & Early Joint Changes

Grant number: 628850 | Funding period: 2010 - 2013

Completed

Abstract

Individuals who have undergone a knee reconstruction are at increased risk of knee osteoarthritis - 'younger people with older knees'. This may be partly due to increased knee load. This study aims to investigate whether muscle strength and activation as well as walking patterns influence changes in the knee joint structure as measured on magnetic resonance imaging. This may lead to rehabilitation strategies to address these factors so as to prevent the premature onset of knee osteoarthritis.

Related publications (11)

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Quadriceps muscle strength at 2 years following anterior cruciate ligament reconstruction is associated with tibiofemoral joint cartilage volume

A Hipsley, M Hall, DJ Saxby, KL Bennell, X Wang, AL Bryant

2022-06-01

Purpose: Quadriceps strength deficits following anterior cruciate ligament reconstruction (ACLR) are linked to altered lower extre..

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Patellar cartilage increase following ACL reconstruction with and without meniscal pathology: a two-year prospective MRI morphological study

X Wang, KL Bennell, Y Wang, K Fortin, DJ Saxby, BA Killen, TV Wrigley, FM Cicuttini, A Van Ginckel, DG Lloyd, JA Feller, CJ Vertullo, T Whitehead, P Gallie, AL Bryant

2021-12-01

Background: Anterior cruciate ligament reconstruction (ACLR) together with concomitant meniscal injury are risk factors for the de..

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Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology

X Wang, KL Bennell, Y Wang, TV Wrigley, A Van Ginckel, K Fortin, DJ Saxby, FM Cicuttini, DG Lloyd, CJ Vertullo, JA Feller, T Whitehead, P Gallie, AL Bryant

2019-07-04

Background: People who have had anterior cruciate ligament reconstruction (ACLR) are at a high risk of developing tibiofemoral joi..

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Greater magnitude tibiofemoral contact forces are associated with reduced prevalence of osteochondral pathologies 2–3 years following anterior cruciate ligament reconstruction

DJ Saxby, AL Bryant, A Van Ginckel, Y Wang, X Wang, L Modenese, P Gerus, JM Konrath, K Fortin, TV Wrigley, KL Bennell, FM Cicuttini, C Vertullo, JA Feller, T Whitehead, P Gallie, DG Lloyd

2019-03-14

Purpose: External loading of osteoarthritic and healthy knees correlates with current and future osteochondral tissue state. These..

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Individual muscle contributions to tibiofemoral compressive articular loading during walking, running and sidestepping

BA Killen, DJ Saxby, K Fortin, BS Gardiner, TV Wrigley, AL Bryant, DG Lloyd

2018-10-26

The tibiofemoral joint (TFJ) experiences large compressive articular contact loads during activities of daily living, caused by in..

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Cartilage quantitative T2 relaxation time 2–4 years following isolated anterior cruciate ligament reconstruction

X Wang, TV Wrigley, KL Bennell, Y Wang, K Fortin, FM Cicuttini, DG Lloyd, AL Bryant

2018-07-01

Cartilage T2 relaxation time in isolated anterior cruciate ligament reconstruction (ACLR) without concomitant meniscal pathology a..

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Relationships Between Tibiofemoral Contact Forces and Cartilage Morphology at 2 to 3 Years After Single-Bundle Hamstring Anterior Cruciate Ligament Reconstruction and in Healthy Knees

DJ Saxby, AL Bryant, X Wang, L Modenese, P Gerus, JM Konrath, KL Bennell, K Fortin, T Wrigley, FM Cicuttini, CJ Vertullo, JA Feller, T Whitehead, P Gallie, DG Lloyd

2017-08-21

Background: Prevention of knee osteoarthritis (OA) following anterior cruciate ligament (ACL) rupture and reconstruction is vital...

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Cartilage morphology at 2–3 years following anterior cruciate ligament reconstruction with or without concomitant meniscal pathology

X Wang, Y Wang, KL Bennell, TV Wrigley, FM Cicuttini, K Fortin, DJ Saxby, A Van Ginckel, AR Dempsey, N Grigg, C Vertullo, JA Feller, T Whitehead, DG Lloyd, AL Bryant

2017-02-01

Purpose: To examine differences in cartilage morphology between young adults 2–3 years post-anterior cruciate ligament reconstruct..

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Tibiofemoral contact forces in the anterior cruciate ligament-reconstructed knee

DJ Saxby, AL Bryant, L Modenese, P Gerus, BA Killen, J Konrath, K Fortin, TV Wrigley, KL Bennell, FM Cicuttini, C Vertullo, JA Feller, T Whitehead, P Gallie, DG Lloyd

2016-11-01

Purpose To investigate differences in anterior cruciate ligament-reconstructed (ACLR) and healthy individuals in terms of the magn..

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Tibiofemoral contact forces during walking, running and sidestepping

DJ Saxby, L Modenese, AL Bryant, P Gerus, B Killen, K Fortin, TV Wrigley, KL Bennell, FM Cicuttini, DG Lloyd

2016-09-01

We explored the tibiofemoral contact forces and the relative contributions of muscles and external loads to those contact forces d..

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Subject-specific knee joint geometry improves predictions of medial tibiofemoral contact forces

P Gerus, M Sartori, TF Besier, BJ Fregly, SL Delp, SA Banks, MG Pandy, DD D'Lima, DG Lloyd

2013-11-15

Estimating tibiofemoral joint contact forces is important for understanding the initiation and progression of knee osteoarthritis...

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