Specific Brain Networks Related to the Symptoms of Obsessive-Compulsive Disorder

Brain alterations in low-frequency fluctuations across multiple bands in obsessive compulsive disorder

Monica Gimenez, Andres Guinea-Izquierdo, Victoria Villalta-Gil, Ignacio Martinez-Zalacain, Cinto Segalas, Marta Subira, Eva Real, Jesus Pujol, Ben J Harrison, Josep Maria Haro, Joao R Sato, Marcelo Q Hoexter, Narcis Cardoner, Pino Alonso, Jose Manuel Menchon, Carles Soriano-Mas

2017-12-01

The extent of functional abnormalities in frontal-subcortical circuits in obsessive-compulsive disorder (OCD) is still unclear. Al..

Attenuated frontal and sensory inputs to the basal ganglia in cannabis users

Laura Blanco-Hinojo, Jesus Pujol, Ben J Harrison, Didac Macia, Albert Batalla, Santiago Nogue, Marta Torrens, Magi Farre, Joan Deus, Rocio Martin-Santos

2017-07-01

Heavy cannabis use is associated with reduced motivation. The basal ganglia, central in the motivation system, have the brain's hi..

Anomalous basal ganglia connectivity and obsessive-compulsive behaviour in patients with Prader Willi syndrome

Jesus Pujol, Laura Blanco-Hinojo, Susanna Esteba-Castillo, Assumpta Caixas, Ben J Harrison, Marta Bueno, Joan Deus, Mercedes Rigla, Didac Macia, Jone Llorente-Onaindia, Ramon Novell-Alsina

2016-07-01

BACKGROUND: Prader Willi syndrome is a genetic disorder with a behavioural expression characterized by the presence of obsessive-c..

Neurodevelopmental correlates of proneness to guilt and shame in adolescence and early adulthood

Sarah Whittle, Kirra Liu, Coralie Bastin, Ben J Harrison, Christopher G Davey

2016-06-01

Investigating how brain development during adolescence and early adulthood underlies guilt- and shame-proneness may be important f..

Cortical Representations of Cognitive Control and Working Memory Are Dependent Yet Non-Interacting

Ian H Harding, Ben J Harrison, Michael Breakspear, Christos Pantelis, Murat Yuecel

2016-02-01

Cognitive control (CC) and working memory (WM) are concurrently necessary for adaptive human behavior. These processes are thought..

Aetiological overlap between obsessive-compulsive related and anxiety disorder symptoms: multivariate twin study

Clara Lopez-Sola, Leonardo F Fontenelle, Minh Bui, John L Hopper, Christos Pantelis, Murat Yuecel, Jose M Menchon, Pino Alonso, Ben J Harrison

2016-01-01

BACKGROUND: The aetiological boundary between obsessive-compulsive related disorders (OCRDs) including obsessive-compulsive disord..

Brain Functional Correlates of Emotion Regulation Across Adolescence and Young Adulthood

Katerina Stephanou, Christopher G Davey, Rebecca Kerestes, Sarah Whittle, Jesus Pujol, Murat Yuecel, Alex Fornito, Marina Lopez-Sola, Ben J Harrison

2016-01-01

Few studies have examined the neural correlates of emotion regulation across adolescence and young adulthood. Existing studies of ..

Functional Connectivity Bias in the Prefrontal Cortex of Psychopaths

Oren Contreras-Rodriguez, Jesus Pujol, Iolanda Batalla, Ben J Harrison, Carles Soriano-Mas, Joan Deus, Marina Lopez-Sola, Didac Macia, Vanessa Pera, Rosa Hernandez-Ribas, Josep Pifarre, Jose M Menchon, Narcis Cardoner

2015-11-01

BACKGROUND: Psychopathy is characterized by a distinctive interpersonal style that combines callous-unemotional traits with inflex..

A Neural Mediator of Human Anxiety Sensitivity

Ben J Harrison, Miquel A Fullana, Carles Soriano-Mas, Esther Via, Jesus Pujol, Ignacio Martinez-Zalacain, Daniella Tinoco-Gonzalez, Christopher G Davey, Marina Lopez-Sola, Victor Perez Sola, Jose M Menchon, Narcis Cardoner

2015-10-01

Advances in the neuroscientific understanding of bodily autonomic awareness, or interoception, have led to the hypothesis that hum..

Abnormal Social Reward Responses in Anorexia Nervosa: An fMRI Study

Esther Via, Carles Soriano-Mas, Isabel Sanchez, Laura Forcano, Ben J Harrison, Christopher G Davey, Jesus Pujol, Ignacio Martinez-Zalacain, Jose M Menchon, Fernando Fernandez-Aranda, Narcis Cardoner

2015-07-21

Patients with anorexia nervosa (AN) display impaired social interactions, implicated in the development and prognosis of the disor..

Discrete Alterations of Brain Network Structural Covariance in Individuals at Ultra-High Risk for Psychosis

Kareen Heinze, Renate LEP Reniers, Barnaby Nelson, Alison R Yung, Ashleigh Lin, Ben J Harrison, Christos Pantelis, Dennis Velakoulis, Patrick D McGorry, Stephen J Wood

2015-06-01

BACKGROUND: Investigation of aberrant large-scale brain networks offers novel insight into the role these networks play in diverse..

Functional brain-imaging correlates of negative affectivity and the onset of first-episode depression

CG Davey, S Whittle, BJ Harrison, JG Simmons, ML Byrne, OS Schwartz, NB Allen

2015-04-01

BACKGROUND: The amygdala and subgenual anterior cingulate cortex (sACC) are key brain regions for the generation of negative affec..

A selective involvement of putamen functional connectivity in youth with internet gaming disorder

Soon-Beom Hong, Ben J Harrison, Orwa Dandash, Eun-Jung Choi, Seong-Chan Kim, Ho-Hyun Kim, Do-Hyun Shim, Chang-Dai Kim, Jae-Won Kim, Soon-Hyung Yi

2015-03-30

Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a re..

Effective connectivity within the frontoparietal control network differentiates cognitive control and working memory

Ian H Harding, Murat Yuecel, Ben J Harrison, Christos Pantelis, Michael Breakspear

2015-02-01

Cognitive control and working memory rely upon a common fronto-parietal network that includes the inferior frontal junction (IFJ),..

Hoarding pet animals in obsessive-compulsive disorder

Andre L Campos-Lima, Albina R Torres, Murat Yuecel, Ben J Harrison, Jorge Moll, Gabriela M Ferreira, Leonardo F Fontenelle

2015-02-01

BACKGROUND: Although severe hoarding symptoms have been considered rare among obsessive-compulsive disorder (OCD) samples, the pre..

Selective Augmentation of Striatal Functional Connectivity Following NMDA Receptor Antagonism: Implications for Psychosis

Orwa Dandash, Ben J Harrison, Ram Adapa, Raphael Gaillard, Francesco Giorlando, Stephen J Wood, Paul C Fletcher, Alex Fornito

2015-02-01

The psychotomimetic effect of the N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine is thought to arise from a functional ..

Functional dysconnectivity of corticostriatal circuitry and differential response to methylphenidate in youth with attention-deficit/hyperactivity disorder

Soon-Beom Hong, Ben J Harrison, Alex Fornito, Chul-Ho Sohn, In-Chan Song, Jae-Won Kim

2015-01-01

BACKGROUND: Brain frontostriatal circuits have been implicated in the pathophysiology of attention-deficit/hyperactivity disorder ..

The neural cascade of olfactory processing: A combined fMRI-EEG study

Yuri Masaoka, Ian H Harding, Nobuyoshi Koiwa, Masaki Yoshida, Ben J Harrison, Valentina Lorenzetti, Masahiro Ida, Masahiko Izumizaki, Christos Pantelis, Ikuo Homma

2014-12-01

Olfaction is dependent on respiration for the delivery of odorants to the nasal cavity. Taking advantage of the time-locked nature..

The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): study protocol for a randomised control trial

Christopher G Davey, Andrew M Chanen, Sue M Cotton, Sarah E Hetrick, Melissa J Kerr, Michael Berk, Olivia M Dean, Kally Yuen, Mark Phelan, Aswin Ratheesh, Miriam R Schaefer, G Paul Amminger, Alexandra G Parker, Danijela Piskulic, Susy Harrigan, Andrew J Mackinnon, Ben J Harrison, Patrick D McGorry

2014-11-04

BACKGROUND: The aim of the Youth Depression Alleviation-Combined Treatment (YoDA-C) study is to determine whether antidepressant m..

Altered Functional Magnetic Resonance Imaging Responses to Nonpainful Sensory Stimulation in Fibromyalgia Patients

Marina Lopez-Sola, Jesus Pujol, Tor D Wager, Alba Garcia-Fontanals, Laura Blanco-Hinojo, Susana Garcia-Blanco, Violant Poca-Dias, Ben J Harrison, Oren Contreras-Rodriguez, Jordi Monfort, Ferran Garcia-Fructuoso, Joan Deus

2014-11-01

OBJECTIVE: Fibromyalgia (FM) is a disorder characterized by chronic pain and enhanced responses to acute noxious events. However, ..

Disruption of brain white matter microstructure in women with anorexia nervosa

Esther Via, Andrew Zalesky, Isabel Sanchez, Laura Forcano, Ben J Harrison, Jesus Pujol, Fernando Fernandez-Aranda, Jose Manuel Menchon, Carles Soriano-Mas, Narcis Cardoner, Alex Fornito

2014-11-01

BACKGROUND: The etiology of anorexia nervosa is still unknown. Multiple and distributed brain regions have been implicated in its ..

Does motion-related brain functional connectivity reflect both artifacts and genuine neural activity?

Jesus Pujol, Didac Macia, Laura Blanco-Hinojo, Gerard Martinez-Vilavella, Jordi Sunyer, Rafael de la Torre, Assumpta Caixas, Rocio Martin-Santos, Joan Deus, Ben J Harrison

2014-11-01

Imaging research on functional connectivity is uniquely contributing to characterize the functional organization of the human brai..

The contribution of sensory system functional connectivity reduction to clinical pain in fibromyalgia

Jesus Pujol, Didac Macia, Alba Garcia-Fontanals, Laura Blanco-Hinojo, Marina Lopez-Sola, Susana Garcia-Blanco, Violant Poca-Dias, Ben J Harrison, Oren Contreras-Rodriguez, Jordi Monfort, Ferran Garcia-Fructuoso, Joan Deus

2014-08-01

Fibromyalgia typically presents with spontaneous body pain with no apparent cause and is considered pathophysiologically to be a f..

Time-resolved resting-state brain networks

Andrew Zalesky, Alex Fornito, Luca Cocchi, Leonardo L Gollo, Michael Breakspear

2014-07-15

Neuronal dynamics display a complex spatiotemporal structure involving the precise, context-dependent coordination of activation p..

Altered Striatal Functional Connectivity in Subjects With an At-Risk Mental State for Psychosis

Orwa Dandash, Alex Fornito, Jimmy Lee, Richard SE Keefe, Michael WL Chee, R Alison Adcock, Christos Pantelis, Stephen J Wood, Ben J Harrison

2014-07-01

Recent functional imaging work in individuals experiencing an at-risk mental state (ARMS) for psychosis has implicated dorsal stri..

Modulation of brain structure by catechol-O-methyltransferase Val(158)Met polymorphism in chronic cannabis users

Albert Batalla, Carles Soriano-Mas, Marina Lopez-Sola, Marta Torrens, Jose A Crippa, Sagnik Bhattacharyya, Laura Blanco-Hinojo, Ana B Fagundo, Ben J Harrison, Santiago Nogue, Rafael de la Torre, Magi Farre, Jesus Pujol, Rocio Martin-Santos

2014-07-01

Neuroimaging studies have shown that chronic consumption of cannabis may result in alterations in brain morphology. Recent work fo..

The Psychiatric Facet of Hyperhidrosis: Demographics, Disability, Quality of Life, and Associated Psychopathology

Larissa da R Lessa, Flavio B Luz, Rebeca M de Rezende, Sandra M Duraes, Ben J Harrison, Gabriela B de Menezes, Leonardo F Fontenelle

2014-07-01

We compared the sociodemographic and psychiatric features of treatment-seeking patients with (n=17) and without (n=29) primary hyp..

Prevalence and Heritability of Obsessive-Compulsive Spectrum and Anxiety Disorder Symptoms: A Survey of the Australian Twin Registry

Clara Lopez-Sola, Leonardo F Fontenelle, Pino Alonso, Daniel Cuadras, Debra L Foley, Christos Pantelis, Jesus Pujol, Murat Yuecel, Narcis Cardoner, Carles Soriano-Mas, Jose M Menchon, Ben J Harrison

2014-06-01

While past twin studies indicate moderate levels of heritability of "obsessive-compulsive related" and anxiety disorder symptoms, ..

Brain structural imaging correlates of olfactory dysfunction in obsessive-compulsive disorder

Cinto Segalas, Pino Alonso, Arantxa Orbegozo, Eva Real, Marta Subira, Clara Lopez-Sola, Ignacio Martinez-Zalacain, Javier Labad, Ben J Harrison, Jesus Pujol, Jose M Menchon, Narcis Cardoner, Carles Soriano-Mas

2014-04-01

Olfactory dysfunction has been described in obsessive-compulsive disorder (OCD). Brain regions involved in smell processing partia..

Functional connectivity alterations in brain networks relevant to self-awareness in chronic cannabis users

Jesus Pujol, Laura Blanco-Hinojo, Albert Batalla, Marina Lopez-Sola, Ben J Harrison, Carles Soriano-Mas, Jose A Crippa, Ana B Fagundo, Joan Deus, Rafael de la Torre, Santiago Nogue, Magi Farre, Marta Torrens, Rocio Martin-Santos

2014-04-01

BACKGROUND: Recreational drugs are generally used to intentionally alter conscious experience. Long-lasting cannabis users frequen..

Amygdala activation and symptom dimensions in obsessive compulsive disorder

Esther Via, Narcis Cardoner, Jesus Pujol, Pino Alonso, Marina Lopez-Sola, Eva Real, Oren Contreras-Rodriguez, Joan Deus, Cinto Segalas, Jose M Menchon, Carles Soriano-Mas, Ben J Harrison

2014-01-01

BACKGROUND: Despite knowledge of amygdala involvement in fear and anxiety, its contribution to the pathophysiology of obsessive-co..

Functional brain imaging studies of youth depression: A systematic review

R Kerestes, CG Davey, K Stephanou, SL Whittle, BJ Harrison

2014-01-01

BACKGROUND: There is growing interest in understanding the neurobiology of major depressive disorder (MDD) in youth, particularly ..

Neural correlates of obsessive-compulsive related dysfunctional beliefs

Pino Alonso, Arantxa Orbegozo, Jesus Pujol, Clara Lopez-Sola, Miquel Angel Fullana, Cinto Segalas, Eva Real, Marta Subira, Ignacio Martinez-Zalacain, Jose M Menchon, Ben J Harrison, Narcis Cardoner, Carles Soriano-Mas

2013-12-02

There have been few attempts to integrate neurobiological and cognitive models of obsessive-compulsive disorder (OCD), although th..

Functional Dysconnectivity of Corticostriatal Circuitry as a Risk Phenotype for Psychosis

Alex Fornito, Ben J Harrison, Emmeline Goodby, Anna Dean, Cinly Ooi, Pradeep J Nathan, Belinda R Lennox, Peter B Jones, John Suckling, Edward T Bullmore

2013-11-01

IMPORTANCE: Dysregulation of corticostriatal circuitry has long been thought to be critical in the etiology of psychotic disorders..

Hatred of sounds: Misophonic disorder or just an underreported psychiatric symptom?

Gabriela M Ferreira, Ben J Harrison, Leonardo F Fontenelle

2013-11-01

BACKGROUND: Misophonia, or selective sound sensitivity syndrome, is a preoccupation with or aversion to certain types of sounds th..

Cognitive impairment in euthymic major depressive disorder: a meta-analysis

E Bora, BJ Harrison, M Yuecel, C Pantelis

2013-10-01

BACKGROUND: There is evidence to suggest that cognitive deficits might persist beyond the acute stages of illness in major depress..

Brain Structural Alterations in Obsessive-Compulsive Disorder Patients with Autogenous and Reactive Obsessions

Marta Subira, Pino Alonso, Cinto Segalas, Eva Real, Clara Lopez-Sola, Jesus Pujol, Ignacio Martinez-Zalacain, Ben J Harrison, Jose M Menchon, Narcis Cardoner, Carles Soriano-Mas

2013-09-30

Obsessive-compulsive disorder (OCD) is a clinically heterogeneous condition. Although structural brain alterations have been consi..

Structural covariance of the neostriatum with regional gray matter volumes

C Soriano-Mas, BJ Harrison, J Pujol, M Lopez-Sola, R Hernandez-Ribas, P Alonso, O Contreras-Rodriguez, M Gimenez, L Blanco-Hinojo, H Ortiz, J Deus, JM Menchon, N Cardoner

2013-05-01

The caudate and putamen nuclei have been traditionally divided into dorsal and ventral territories based on their segregated patte..

Neural response to the observable self in social anxiety disorder

J Pujol, M Gimenez, H Ortiz, C Soriano-Mas, M Lopez-Sola, M Farre, J Deus, E Merlo-Pich, BJ Harrison, N Cardoner, R Navines, R Martin-Santos

2013-04-01

BACKGROUND: Distorted images of the observable self are considered crucial in the development and maintenance of social anxiety. W..

Brain Corticostriatal Systems and the Major Clinical Symptom Dimensions of Obsessive-Compulsive Disorder

Ben J Harrison, Jesus Pujol, Narcis Cardoner, Joan Deus, Pino Alonso, Marina Lopez-Sola, Oren Contreras-Rodriguez, Eva Real, Cinto Segalas, Laura Blanco-Hinojo, Jose M Menchon, Carles Soriano-Mas

2013-02-15

BACKGROUND: Functional neuroimaging studies have provided consistent support for the idea that obsessive-compulsive disorder (OCD)..

Breakdown in the brain network subserving moral judgment in criminal psychopathy

Jesus Pujol, Iolanda Batalla, Oren Contreras-Rodriguez, Ben J Harrison, Vanessa Pera, Rosa Hernandez-Ribas, Eva Real, Laura Bosa, Carles Soriano-Mas, Joan Deus, Marina Lopez-Sola, Josep Pifarre, Jose M Menchon, Narcis Cardoner

2012-11-01

Neuroimaging research has demonstrated the involvement of a well-defined brain network in the mediation of moral judgment in norma..

Regionally specific alterations in functional connectivity of the anterior cingulate cortex in major depressive disorder

CG Davey, BJ Harrison, M Yuecel, NB Allen

2012-10-01

BACKGROUND: Depression has been associated with functional alterations in several areas of the cingulate cortex. In this study we ..

Competitive and cooperative dynamics of large-scale brain functional networks supporting recollection

Alex Fornito, Ben J Harrison, Andrew Zalesky, Jon S Simons

2012-07-31

Analyses of functional interactions between large-scale brain networks have identified two broad systems that operate in apparent ..

Brain functional connectivity during induced sadness in patients with obsessive-compulsive disorder

Leonardo F Fontenelle, Ben J Harrison, Jesus Pujol, Christopher G Davey, Alex Fornito, Emre Bora, Christos Pantelis, Murat Yuecel

2012-07-01

BACKGROUND: Obsessive-compulsive disorder (OCD) is associated with a range of emotional abnormalities linked to its defining sympt..

Functional Connectivity in Brain Networks Underlying Cognitive Control in Chronic Cannabis Users

Ian H Harding, Nadia Solowij, Ben J Harrison, Michael Takag, Valentina Lorenzetti, Dan I Lubman, Marc L Seal, Christos Pantelis, Murat Yuecel

2012-07-01

The long-term effect of regular cannabis use on brain function underlying cognitive control remains equivocal. Cognitive control a..

Neural Correlates of Moral Sensitivity in Obsessive-Compulsive Disorder

Ben J Harrison, Jesus Pujol, Carles Soriano-Mas, Rosa Hernandez-Ribas, Marina Lopez-Sola, Hector Ortiz, Pino Alonso, Joan Deus, Jose M Menchon, Eva Real, Cinto Segalas, Oren Contreras-Rodriguez, Laura Blanco-Hinojo, Narcis Cardoner

2012-07-01

CONTEXT: Heightened moral sensitivity seems to characterize patients with obsessive-compulsive disorder (OCD). Recent advances in ..

Meta-analysis of volumetric abnormalities in cortico-striatal-pallidal-thalamic circuits in major depressive disorder

E Bora, BJ Harrison, CG Davey, M Yuecel, C Pantelis

2012-04-01

BACKGROUND: Abnormalities in cortico-striatal-pallidal-thalamic (CSPT) circuits have been implicated in major depressive disorder ..

Towards a post-traumatic subtype of obsessive-compulsive disorder

Leonardo F Fontenelle, Luca Cocchi, Ben J Harrison, Roseli G Shavitt, Maria Conceicao do Rosario, Ygor A Ferrao, Maria Alice de Mathis, Aristides V Cordioli, Murat Yuecel, Christos Pantelis, Jair de Jesus Mari, Euripedes C Miguel, Albina R Torres

2012-03-01

We evaluated whether traumatic events are associated with a distinctive pattern of socio-demographic and clinical features of obse..

Brain connectivity and mental illness.

Alex Fornito, Ben J Harrison

2012-01-01

Task-related deactivation and functional connectivity of the subgenual cingulate cortex in major depressive disorder.

Christopher G Davey, Murat Yücel, Nicholas B Allen, Ben J Harrison

2012-01-01

BACKGROUND: Major depressive disorder is associated with functional alterations in activity and resting-state connectivity of the ..

White matter microstructure in opiate addiction

Emre Bora, Murat Yuecel, Alex Fornito, Christos Pantelis, Ben J Harrison, Luca Cocchi, Gaby Pell, Dan I Lubman

2012-01-01

Heroin addiction has been associated with impaired neuronal connectivity and cognitive deficits. One mechanism that potentially ex..

Enhanced brain responsiveness during active emotional face processing in obsessive compulsive disorder

Narcis Cardoner, Ben J Harrison, Jesus Pujol, Carles Soriano-Mas, Rosa Hernandez-Ribas, Marina Lopez-Sola, Eva Real, Joan Deus, Hector Ortiz, Pino Alonso, Jose M Menchon

2011-08-01

OBJECTIVES. The abnormal processing of emotional stimuli is common to a variety of psychiatric disorders. Specifically, patients w..

Increased Amygdala Response to Positive Social Feedback in Young People with Major Depressive Disorder

Christopher G Davey, Nicholas B Allen, Ben J Harrison, Murat Yuecel

2011-04-15

BACKGROUND: Studies of depressed patients have demonstrated increased amygdala activation to negative affective stimuli. In this s..

Cross-Sectional and Longitudinal Assessment of Structural Brain Alterations in Melancholic Depression

Carles Soriano-Mas, Rosa Hernandez-Ribas, Jesus Pujol, Mikel Urretavizcaya, Joan Deus, Ben J Harrison, Hector Ortiz, Marina Lopez-Sola, Josep M Menchon, Narcis Cardoner

2011-02-15

BACKGROUND: Whole-brain imaging approaches may contribute to the characterization of neuroanatomic alterations in major depression..

Role of stressful and traumatic life events in obsessive-compulsive disorder

Leonardo F Fontenelle, Luca Cocchi, Ben J Harrison, Euripedes C Miguel, Albina R Torres

2011-02-01

Whilst genetic factors are thought to contribute to the development of obsessive-compulsive disorder (OCD), the role of environmen..

White matter microstructure in patients with obsessive-compulsive disorder

Emre Bora, Ben J Harrison, Alex Fornito, Luca Cocchi, Jesus Pujol, Leonardo F Fontenelle, Dennis Velakoulis, Christos Pantelis, Murat Yuecel

2011-01-01

BACKGROUND: Previous diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD) have reported inc..

Effects of Duloxetine Treatment on Brain Response to Painful Stimulation in Major Depressive Disorder

Marina Lopez-Sola, Jesus Pujol, Rosa Hernandez-Ribas, Ben J Harrison, Oren Contreras-Rodriguez, Carles Soriano-Mas, Joan Deus, Hector Ortiz, Jose M Menchon, Julio Vallejo, Narcis Cardoner

2010-10-01

Major depressive disorder (MDD) is characterized by a constellation of affective, cognitive, and somatic symptoms associated with ..