Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications
Grant number: DP1094147 | Funding period: 2010 - 2013
The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surface coatings, films and advanced particles, leading to significant outcomes in diverse areas, including drug delivery, biomaterial implants and biocatalysis. The project will contribute to the development of a robust Australian nanotechnology industry, with the advanced materials developed expected..View full description
Related publications (14)
Tuning the Properties of Polymer Capsules for Cellular Interactions
Huanli Sun, Jiwei Cui, Yi Ju, Xi Chen, Edgar HH Wong, Jenny Tran, Greg G Qiao, Frank Caruso
Particle-cell interactions are governed by, among other factors, the composition and surface properties of the particles. Herein, ..
Photocontrolled Cargo Release from Dual Cross-Linked Polymer Particles
Shereen Tan, Jiwei Cui, Qiang Fu, Eunhyung Nam, Katharina Ladewig, Jing M Ren, Edgar HH Wong, Frank Caruso, Anton Blencowe, Greg G Qiao
Burst release of a payload from polymeric particles upon photoirradiation was engineered by altering the cross-linking density. Th..
Structure Governs the Deformability of Polymer Particles in a Microfluidic Blood Capillary Model
Huanli Sun, Mattias Bjoernmalm, Jiwei Cui, Edgar HH Wong, Yunlu Dai, Qiong Dai, Greg G Qiao, Frank Caruso
Particle stiffness is a design parameter that affects bionano interactions, including biodistribution kinetics and cellular proces..
Fabrication of ultra-thin polyrotaxane-based films via solid-state continuous assembly of polymers
Shereen Tan, Eunhyung Nam, Jiwei Cui, Chenglong Xu, Qiang Fu, Jing M Ren, Edgar HH Wong, Katharina Ladewig, Frank Caruso, Anton Blencowe, Greg G Qiao
Surface-confined ultra-thin polyrotaxane (PRX)-based films with tunable composition, surface topology and swelling characteristics..
Fabrication of Chiral Stationary Phases via Continuous Assembly of Polymers for Resolution of Enantiomers by Liquid Chromatography
Stefanie N Guntari, Eunhyung Nam, Nina N Pranata, Kenneth Chia, Edgar HH Wong, A Blencowe, Tor K Goh, Frank Caruso, Greg G Qiao
Precise stereochemical determination of chiral molecules is highly important, especially in the pharmaceutical industry where one ..
Continuous assembly of polymers via solid phase reactions
Eunhyung Nam, Jinguk Kim, Stefanie N Guntari, Helga Seyler, Qiang Fu, Edgar HH Wong, Anton Blencowe, David J Jones, Frank Caruso, Greg G Qiao
The continuous assembly of polymers in the solid state via ring-opening metathesis polymerization (ssCAPROMP) is reported as an ef..
(Super)hydrophobic and Multilayered Amphiphilic Films Prepared by Continuous Assembly of Polymers
Stefanie N Guntari, Aaron CH Khin, Edgar HH Wong, Tor K Goh, Anton Blencowe, Frank Caruso, Greg G Qiao
The continuous assembly of polymers (CAP) is used to fabricate tailored nanocoatings on a wide variety of substrates. Ring-opening..
Assembly of Nanostructured Films with Hydrophobic Subcompartments via Continuous Assembly of Polymers
Edgar HH Wong, Martin P van Koeverden, Eunhyung Nam, Stefanie N Guntari, Steven Harris Wibowo, Anton Blencowe, Frank Caruso, Greg G Qiao
The generation of nanoscale polymer films using complex, hierarchically structured (bio)macromolecular architectures has important..
Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers
Stefanie N Guntari, Edgar HH Wong, Tor K Goh, Rona Chandrawati, Anton Blencowe, Frank Caruso, Greg G Qiao
We report that the continuous assembly of polymers (CAP) approach, mediated by ring-opening metathesis polymerization (ROMP), is a..
Factors influencing the growth and topography of nanoscale films fabricated by ROMP-mediated continuous assembly of polymers
Stefanie N Guntari, Tor K Goh, Anton Blencowe, Edgar HH Wong, Frank Caruso, Greg G Qiao
The continuous assembly of polymers (CAP) mediated via ring-opening metathesis polymerization (ROMP) is demonstrated as a simple a..
Ultrathin, bioresponsive and drug-functionalized protein capsules
Damien Mertz, Huixi Wu, Jy Shyuan Wong, Jiwei Cui, Pramudana Tan, Roxane Alles, Frank Caruso
This paper presents a versatile approach for the synthesis of ultrathin (ca. 10 nm thickness) and bioresponsive protein capsules. ..
Phototriggered, Metal-Free Continuous Assembly of Polymers for the Fabrication of Ultrathin Films
Edgar HH Wong, Stefanie N Guntari, Anton Blencowe, Martin P van Koeverden, Frank Caruso, Greg G Qiao
A facile and metal-free thin film fabrication technology based on the photoinduced continuous assembly of polymers (photoCAP) is d..
Nanoengineered Films via Surface-Confined Continuous Assembly of Polymers
Tor Kit Goh, Stefanie N Guntari, Christopher J Ochs, Anton Blencowe, Damien Mertz, Luke A Connal, Georgina K Such, Greg G Qiao, Frank Caruso
A highly generalizable, surface-confined, continuous polymer assembly process, amenable to various substrates, reaction conditions..