Small Molecule X-ray Molecular Structure Elucidation Facility

Structures of the hydrate and dihydrate forms of the DNA-binding radioprotector methylproamine

Jonathan Michael White, Samuel Charles Brydon, Thomas Fellowes

2018-12-01

Methyl pro­amine {N,N,3-trimethyl-4-[6-(4-methyl­piperazin-1-yl)-1H,3′H-[2,5′-bibenzo[d]imidazol]-2′-yl]aniline}, C28H35N7O2, crys..

Models for aerobic carbon monoxide dehydrogenase: synthesis, characterization and reactivity of paramagnetic (MoO)-O-V(mu-S)Cu-I complexes

Craig Gourlay, David J Nielsen, David J Evans, Jonathan M White, Charles G Young

2018-01-28

Reaction of [CoCp2][TpiPrMoOS(OAr)] [Cp = η5-cyclopentadienyl; TpiPr = hydrotris(3-isopropylpyrazol-1-yl)borate; OAr = phenolate o..

Gram scale preparation of clozapine N-oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs

Phillip L van der Peet, Christian Gunawan, Alaa Abdul-Ridha, Sherie Ma, Daniel J Scott, Andrew L Gundlach, Ross AD Bathgate, Jonathan M White, Spencer J Williams

2018-01-01

Chemogenetics uses engineered proteins that are controlled by small molecule actuators, allowing in vivo functional studies of pro..

X-ray crystal structural and spectral studies of copper(II) and nickel(II) complexes of two asymmetric bis(thiosemicarbazone) ligands and the investigation of relationship between the N(4)-substituent and the electrochemical behavior

Sara Hosseinpour, Seyed Abolfazl Hosseini-Yazdi, Jonathan White, W Scott Kassel, Nicholas A Piro

2017-01-10

Asymmetric, potentially tetradentate ligands (H2L5, H2L6·2MeOH) are formed by subsequent condensation a 4-chlorophenyl thiosemicar..

Synthesis, characterization, and X-ray crystal structures of copper(II) and nickel(II) complexes with two bis(thiosemicarbazone) ligands and investigation of their electrochemical behavior

Seyed Abolfazl Hosseini-Yazdi, Sara Hosseinpour, Ali Akbar Khandar, Jonathan White

2016-02-01

Two new bis(thiosemicarbazone) ligands having a halogen substituent on the non-coordinating phenyl rings, namely 2-[1-(2-{3-[2-({2..

Synthesis, X-ray crystal structure, thermal behavior and spectroscopic analysis of 1-(1-naphthoyl)-3-(halo-phenyl)-thioureas complemented with quantum chemical calculations

Aamer Saeed, Saba Ashraf, Jonathan M White, Delia B Soria, Carlos A Franca, Mauricio F Erben

2015-11-05

Two novel 1-(1-naphthoyl)-3-(halo-phenyl) substituted thioureas, namely 1-(1-naphthoyl)-3-(2,4-di-fluoro-phenyl)-thiourea (1) and ..

Total Synthesis of Ustiloxin D Utilizing an Ammonia-Ugi Reaction

Aaron L Brown, Quentin I Churches, Craig A Hutton

2015-10-16

Total synthesis of the highly functionalized cyclic peptide natural product, ustiloxin D, has been achieved in a convergent manner..

A Transparent Planar Concentrator Using Aggregates of gem-Pyrene Ethenes

James L Banal, Jonathan M White, Tin Wai Lam, Andrew W Blakers, Kenneth P Ghiggino, Wallace WH Wong

2015-10-07

The luminescence properties of pyrene ethenes, both as monomer and aggregate species, are found to depend on the regioisomer struc..

d(1) Oxosulfido-Mo(V) Compounds: First Isolation and Unambiguous Characterization of an Extended Series

Christian J Doonan, Craig Gourlay, David J Nielsen, Victor WL Ng, Paul D Smith, David J Evans, Graham N George, Jonathan M White, Charles G Young

2015-07-06

Reaction of Tp(iPr)Mo(VI)OS(OAr) with cobaltocene in toluene results in the precipitation of brown, microcrystalline oxosulfido-Mo..

The Ionic Charge of Copper-64 Complexes Conjugated to an Engineered Antibody Affects Biodistribution

Jason LJ Dearing, Brett M Paterson, Vamsidhar Akurathi, Soledad Betanzos-Lara, S Ted Treves, Stephan D Voss, Jonathan M White, James S Huston, Suzanne V Smith, Paul S Donnelly, Alan B Packard

2015-04-01

The development of biomolecules as imaging probes requires radiolabeling methods that do not significantly influence their biodist..

Anion influence in the structural diversity of cadmium coordination polymers constructed from a pyridine based Schiff base ligand

Ali Akbar Khandar, Farhad Akbari Afkhami, Seyed Abolfazl Hosseini-Yazdi, Jonathan M White, Scott Kassel, William G Dougherty, Janusz Lipkowski, Donald Van Derveer, Gerald Giester, Ferdinando Costantino

2015-03-01

A series of seven coordination polymers based on Cd and potentially tetradentate pyridine based Schiff base ligand with different ..

1,3-Dipolar cycloaddition reactions of phthalic anhydrides with an azomethine ylide

Hugo Santos, Amy Distiller, Asha M D'Souza, Quentin Arnoux, Jonathan M White, Adam G Meyer, John H Ryan

2015-01-01

A series of phthalic anhydrides underwent a 1,3-dipolar cycloaddition reaction with N-benzylazomethine ylide, formed in situ from ..

A molecular nematic liquid crystalline material for high-performance organic photovoltaics

Kuan Sun, Zeyun Xiao, Shirong Lu, Wojciech Zajaczkowski, Wojciech Pisula, Eric Hanssen, Jonathan M White, Rachel M Williamson, Jegadesan Subbiah, Jianyong Ouyang, Andrew B Holmes, Wallace WH Wong, David J Jones

2015-01-01

Solution-processed organic photovoltaic cells (OPVs) hold great promise to enable roll-to-roll printing of environmentally friendl..

Controlling biofilms on cultural materials: the role of 3-(dodecane-1-thiyl)-4-(hydroxymethyl)-2,2,5,5-tetramethyl-1-pyrrolinoxyl

Stefanie-Ann Alexander, Emma M Rouse, Jonathan M White, Nicole Tse, Caroline Kyi, Carl H Schiesser

2015-01-01

3-(Dodecanethiyl)-4-(hydroxymethyl)-2,2,5,5-tetramethyl-1-pyrrolinoxyl (5) effectively disperses biofilms of relevance to cultural..

Excited state dynamics of organic semi-conducting materials

Kenneth P Ghiggino, Andrew J Tilley, Benjamin Robotham, Jonathan M White

2015-01-01

Time-resolved absorption and emission spectroscopy has been applied to investigate the dynamics of excited state processes in olig..

Exploration of a library of triazolothiadiazole and triazolothiadiazine compounds as a highly potent and selective family of cholinesterase and monoamine oxidase inhibitors: design, synthesis, X-ray diffraction analysis and molecular docking studies

Imtiaz Khan, Syeda Mahwish Bakht, Aliya Ibrar, Saba Abbas, Shahid Hameed, Jonathan M White, Usman Ali Rana, Sumera Zaib, Mohammad Shahid, Jamshed Iqbal

2015-01-01

There is a high demand for the collection of small organic molecules (especially N-heterocycles) with diversity and complexity in ..

Rhenium and technetium complexes that bind to amyloid-beta plaques

David J Hayne, Andrea J North, Michelle Fodero-Tavoletti, Jonathan M White, Lin W Hung, Angela Rigopoulos, Catriona A McLean, Paul A Adlard, Uwe Ackermann, Henri Tochon-Danguy, Victor L Villemagne, Kevin J Barnham, Paul S Donnelly

2015-01-01

Alzheimer's disease is associated with the presence of insoluble protein deposits in the brain called amyloid plaques. The major c..

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

Shane M Hickey, Trent D Ashton, Simren K Khosa, Ryan N Robson, Jonathan M White, Jian Li, Roger L Nation, Heidi Y Yu, Alysha G Elliott, Mark S Butler, Johnny X Huang, Matthew A Cooper, Frederick M Pfeffer

2015-01-01

A series of structurally amphiphilic biscationic norbornanes have been synthesised as rigidified, low molecular weight peptidomime..

Synthesis of norbornane bisether antibiotics via silver-mediated alkylation

Shane M Hickey, Trent D Ashton, Jonathan M White, Jian Li, Roger L Nation, Heidi Y Yu, Alysha G Elliott, Mark S Butler, Johnny X Huang, Matthew A Cooper, Frederick M Pfeffer

2015-01-01

A small series of norbornane bisether diguanidines have been synthesized and evaluated as antibacterial agents. The key transforma..

Synthesis, structure and gas-phase reactivity of the mixed silver hydride boroh dride nanocluster [Ag-3(mu(3)-H)(mu(3)-BH4)L-Ph]BF4 (L-Ph = bis(diphenylphosphino)methane)

Athanasios Zavras, Alireza Ariafard, George N Khairallah, Jonathan M White, Roger J Mulder, Allan J Canty, Richard AJ O'Hair

2015-01-01

Borohydrides react with silver salts to give products that span multiple scales ranging from discrete mononuclear compounds throug..

Total synthesis of ( /-)-nicolaioidesin B via a highly regio- and diastereoselective Diels-Alder reaction

Adam J Pigott, Romain J Lepage, Jonathan M White, Mark J Coster

2014-12-10

The total synthesis of (±)-nicolaioidesin B, a natural product that shows preferential cytotoxicity against pancreatic cancer cell..

Crystal structure of 2-(4-chloro-phen-yl)-2-oxoethyl 3-bromo-benzoate.

Imtiaz Khan, Aliya Ibrar, Shahid Hameed, Jonathan M White, Jim Simpson

2014-11-01

2-(4-Chloro-phen-yl)-2-oxoethyl 3-bromo-benzoate, C15H10BrClO3, was synthesized in a single-step reaction by condensation of 3-bro..

Synthesis, Structural Characterization, and Gas-Phase Unimolecular Reactivity of the Silver Hydride Nanocluster [Ag-3((PPh2)(2)CH2)(3)(mu(3)-H)](BF4)(2)

Athanasios Zavras, George N Khairallah, Timothy U Connell, Jonathan M White, Alison J Edwards, Roger J Mulder, Paul S Donnelly, Richard AJ O'Hair

2014-07-21

A bis(diphenylphosphino)methane-ligated trinuclear silver hydride nanocluster, [Ag3((Ph2P)2CH2)3(μ3-H)](BF4)2, featuring three sil..

Copper and Silver Complexes of Tris(triazole)amine and Tris(benzimidazole)amine Ligands: Evidence that Catalysis of an Azide-Alkyne Cycloaddition ("Click") Reaction by a Silver Tris(triazole)amine Complex Arises from Copper Impurities

Timothy U Connell, Christine Schieber, Ilaria Proietti Silvestri, Jonathan M White, Spencer J Williams, Paul S Donnelly

2014-07-07

The synthesis and characterization of a silver complex of the tripodal triazole ligand, tris(benzyltriazolylmethyl)amine (TBTA, L(..

Simplified Silvestrol Analogues with Potent Cytotoxic Activity

Bill C Hawkins, Lisa M Lindqvist, Nhu Duong, Phillip P Sharp, David Segal, Andrew K Powell, Michael Campbell, Eileen Ryan, Jennifer M Chambers, Jonathan M White, Mark A Rizzacasa, Guillaume Lessene, David CS Huang, Christopher J Burns

2014-07-01

The complex natural products silvestrol (1) and episilvestrol (2) are inhibitors of translation initiation through binding to the ..

Synthesis and Pharmacological Evaluation of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) Designed to Bind Irreversibly to an Allosteric Site of the M-1 Muscarinic Acetylcholine Receptor

Briana J Davie, Celine Valant, Jonathan M White, Patrick M Sexton, Ben Capuano, Arthur Christopoulos, Peter J Scammells

2014-06-26

Activation of the M1 muscarinic acetylcholine receptor (mAChR) is a prospective treatment for alleviating cognitive decline experi..

Morphology Change and Improved Efficiency in Organic Photovoltaics via Hexa-peri-hexabenzocoronene Templates

Henk H Dam, Kuan Sun, Eric Hanssen, Jonathan M White, Tomasz Marszalek, Wojciech Pisula, Jens Czolk, Jens Ludwig, Alexander Colsmann, Marina Pfaff, Dagmar Gerthsen, Wallace WH Wong, David J Jones

2014-06-11

The morphology of the active layer in organic photovoltaics (OPVs) is of crucial importance as it greatly influences charge genera..

Preparation and X-ray analysis of potassium (2,3-dichlorophenyl)glucosinolate

Quan V Vo, Craige Trenerry, Simone Rochfort, Jonathan White, Andrew B Hughes

2014-06-01

There has been much interest in obtaining crystals for crystallographic analysis of biologically active glucosinolates. Crystals o..

Convergent Access to Polycyclic Cyclopentanoids from alpha,beta-Unsaturated Acid Chlorides and Alkynes through a Reductive Coupling, Nazarov Cyclization Sequence

Jason H Chaplin, Kristal Jackson, Jonathan M White, Bernard L Flynn

2014-04-18

Reductive coupling of α,β-unsaturated acid chlorides A with alkynoyls B provides convergent access to Nazarov cyclization precurso..

Concentrating Aggregation-Induced Fluorescence in Planar Waveguides: A Proof-of-Principle

James L Banal, Jonathan M White, Kenneth P Ghiggino, Wallace WH Wong

2014-04-10

The photophysical properties of fluorescent dyes are key determinants in the performance of luminescent solar concentrators (LSCs)..

Understanding Electrogenerated Chemiluminescence Efficiency in Blue-Shifted Iridium(III)-Complexes: An Experimental and Theoretical Study

Gregory J Barbante, Egan H Doeven, Emily Kerr, Timothy U Connell, Paul S Donnelly, Jonathan M White, Thais Lopes, Sarah Laird, David JD Wilson, Peter J Barnard, Conor F Hogan, Paul S Francis

2014-03-17

Compared to tris(2-phenylpyridine)iridium(III) ([Ir(ppy)3 ]), iridium(III) complexes containing difluorophenylpyridine (df-ppy) an..

Synthesis of the C1-C18 Fragment of Rhizopodin: Late-State Introduction of the Oxazole

Tobias Bender, Darran Loits, Jonathan M White, Mark A Rizzacasa

2014-03-07

The synthesis of the C1-C18 fragment of the myxobacteria metabolite rhizopodin is described. Initial attempts at installing the E,..

Mobile Proton Triggered Radical Fragmentation of Nitroarginine Containing Peptides

Michael G Leeming, Jonathan M White, Richard AJ O'Hair, William A Donald

2014-03-01

Protonated nitroarginine, [R(NO2) + H](+), which contains the nitroguanidine 'explosophore,' undergoes homolytic N - N nitro-imine..

Single Isomer of Indene-C-70 Bisadduct-Isolation and Performance in Bulk Heterojunction Solar Cells

Wallace WH Wong, Jegadesan Subbiah, Jonathan M White, Helga Seyler, Bolong Zhang, David J Jones, Andrew B Holmes

2014-02-25

Indene-C70 bisadduct (IC70BA) is a high performance electron acceptor material consisting of a mixture of regioisomers. A single i..

Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate

Rohan J Williams, Javier Iglesias-Fernandez, Judith Stepper, Adam Jackson, Andrew J Thompson, Elisabeth C Lowe, Jonathan M White, Harry J Gilbert, Carme Rovira, Gideon J Davies, Spencer J Williams

2014-01-20

Mannosidases catalyze the hydrolysis of a diverse range of polysaccharides and glycoconjugates, and the various sequence-based man..

Application of the Variable Oxygen Probe to Determine the pi-Electron Donor Ability of the Alkyne Group

Benjamin L Harris, Jonathan M White

2014-01-01

Eight ester and ether derivatives of propargyl alcohol with varying electron demand were structurally characterised using low temp..

Oxidative damage of aromatic dipeptides by the environmental oxidants NO2 center dot and O-3

LF Gamon, JM White, U Wille

2014-01-01

Irreversible oxidative damage at both aromatic side chains and dipeptide linkage occurs in the aromatic N- and C-protected dipepti..

PET imaging of tumours with a Cu-64 labeled macrobicyclic cage amine ligand tethered to Tyr(3)-octreotate

Brett M Paterson, Peter Roselt, Delphine Denoyer, Carleen Cullinane, David Binns, Wayne Noonan, Charmaine M Jeffery, Roger I Price, Jonathan M White, Rodney J Hicks, Paul S Donnelly

2014-01-01

The use of copper radioisotopes in cancer diagnosis and radionuclide therapy is possible using chelators that are capable of bindi..

Rhenium and technetium tricarbonyl complexes of 1,4-substituted pyridyl-1,2,3-triazole bidentate ‘click’ ligands conjugated to a targeting RGD peptide

TU Connell, DJ Hayne, Uwe Ackermann, JM White, PS Donnelly, Henri Tochon-Danguy

2014-01-01

New 1,4‐substituted pyridyl‐1,2,3‐triazole ligands with pendent phenyl isothiocyanate functional groups linked to the heterocycle ..

Total syntheses of cis-cyclopropane fatty acids: dihydromalvalic acid, dihydrosterculic acid, lactobacillic acid, and 9,10-methylenehexadecanoic acid

Sayali Shah, Jonathan M White, Spencer J Williams

2014-01-01

cis-Cyclopropane fatty acids (cis-CFAs) are widespread constituents of the seed oils of subtropical plants, membrane components of..

Phenylphenalenones and oxabenzochrysenones from the Australian plant Haemodorum simulans

Sylvia Urban, Michael A Timmers, Robert Brkljaca, Jonathan M White

2013-11-01

Chemical investigation of the Australian plant Haemodorum simulans (Haemodoraceae) resulted in the isolation of two new phenylphen..

Diagnostic Imaging Agents for Alzheimer's Disease: Copper Radiopharmaceuticals that Target A beta Plaques

James L Hickey, SinChun Lim, David J Hayne, Brett M Paterson, Jonathan M White, Victor L Villemagne, Peter Roselt, David Binns, Carleen Cullinane, Charmaine M Jeffery, Roger I Price, Kevin J Barnham, Paul S Donnelly

2013-10-30

One of the pathological hallmarks of Alzheimer's disease is the presence of amyloid-β plaques in the brain and the major constitue..

Synthesis, characterization and metal ion complexation and extraction capabilities of calix[4]arene Schiff base compounds

James P Ward, Jonathan M White, Charles G Young

2013-10-14

The syntheses, characterization and metal ion complexation and extraction capabilities of six new calix[4]arene Schiff base compou..

Asymmetric Synthesis of ( )- and (-)-Pauciflorol F: Confirmation of Absolute Stereochemistry

Daniel J Kerr, Michael Miletic, Narasimhulu Manchala, Jonathan M White, Bernard L Flynn

2013-08-16

An efficient, formal enantioselective synthesis of (+)- and (-)-pauciflorol F has been achieved using a recently introduced oxazol..

Synthesis, Structure and Gas-Phase Reactivity of a Silver Hydride Complex [Ag-3{(PPh2)(2)CH2}(3)(mu(3)-H)(mu(3)-Cl)]BF4

Athanasios Zavras, George N Khairallah, Timothy U Connell, Jonathan M White, Alison J Edwards, Paul S Donnelly, Richard AJ O'Hair

2013-08-05

Mass spectrometry shows the way! MS analysis of silver salts treated with sodium borohydride in the presence of a bis(phosphino) l..

Synthesis, molecular structure, NMR spectroscopic and computational analysis of a selective adenosine A(2A) antagonist, ZM 241385

Manuela Joerg, Mark Agostino, Elizabeth Yuriev, Frankie S Mak, Neil D Miller, Jonathan M White, Peter J Scammells, Ben Capuano

2013-08-01

Herein, we describe the synthesis of the adenosine A2A antagonist ZM 241385 (9) starting from commercially available 2-furanhydraz..

A Click Chemistry Approach to 5,5 '-Disubstituted-3,3 '-Bisisoxazoles from Dichloroglyoxime and Alkynes: Luminescent Organometallic Iridium and Rhenium Bisisoxazole Complexes

Phillip L van der Peet, Timothy U Connell, Christian Gunawan, Jonathan M White, Paul S Donnelly, Spencer J Williams

2013-07-19

5,5'-Disubstituted-3,3'-bisisoxazoles are prepared in one step by the dropwise addition of aqueous potassium hydrogen carbonate to..

Structural effects of potentially hexadentate Schiff base ligands involving pyrrolic, etheric or thioetheric donors towards zinc(II) cation: Synthesis, characterization and crystal structures

Ali Akbar Khandar, Jonathan White, Tahereh Taghvaee-Yazdeli, Seyed Abolfazl Hosseini-Yazdi, Patrick McArdle

2013-05-01

The three new zinc (II) complexes (ZnLm, m = 1-3) of potentially hexadentate Schiff base ligands containing N4O2 and N4S2 donors w..

Using Distonic Radical Ions to Probe the Chemistry of Key Combustion Intermediates: The Case of the Benzoxyl Radical Anion

Cong Li, Adrian KY Lam, George N Khairallah, Jonathan M White, Richard AJ O'Hair, Gabriel da Silva

2013-04-01

The benzoxyl radical is a key intermediate in the combustion of toluene and other aromatic hydrocarbons, yet relatively little exp..

Halide-ion-templated Ag8Cu6 rhombic dodecahedrons: synthesis, structure and reactivity of [Ag8Cu6(C=CtBu)(12)X]BF4 (X = Cl, Br)

Timothy U Connell, Saman Sandanayake, George N Khairallah, Jonathan M White, Richard AJ O'Hair, Paul S Donnelly, Spencer J Williams

2013-01-01

Halide-templated tert-butylethynide Ag14 complexes undergo reversible exchange with copper(I) to afford a series of mixed Ag14-nCu..

Hyperconjugation involving strained carbon-carbon bonds. Application of the variable oxygen probe to ester and ether derivatives of cubylmethanol

Benjamin Harris, G Paul Savage, Jonathan M White

2013-01-01

Application of the variable oxygen probe to derivatives of (4-methoxycarbonyl)cubylmethanol 11 demonstrated a strong response of C..

Preventing Protein Oxidation with Sugars: Scavenging of Hypohalous Acids by 5-Selenopyranose and 4-Selenofuranose Derivatives

Corin Storkey, David I Pattison, Jonathan M White, Carl H Schiesser, Michael J Davies

2012-11-01

Heme peroxidases including myeloperoxidase (MPO) are released at sites of inflammation by activated leukocytes. MPO generates hypo..

Total Synthesis of 2 ''',5 '''-Diepisilvestrol and Its C1 ''' Epimer: Key Structure Activity Relationships at C1 ''' and C2 '''

Jennifer M Chambers, David CS Huang, Lisa M Lindqvist, G Paul Savage, Jonathan M White, Mark A Rizzacasa

2012-08-01

The first total synthesis of the low-abundance natural product 2''',5'''-diepisilvestrol (4) is described. The key step involved a..

Total Synthesis of Mycocyclosin

James R Cochrane, Jonathan M White, Uta Wille, Craig A Hutton

2012-05-04

The first total synthesis of mycocyclosin, a diketopiperazine natural product isolated from M. tuberculosis, is described. While d..

Oxazolidinone-Promoted, Torquoselective Nazarov Cyclizations

Daniel J Kerr, Michael Miletic, Jason H Chaplin, Jonathan M White, Bernard L Flynn

2012-04-06

Oxazolidinones are powerful promoters of the Nazarov reaction, enabling the cyclization of conventionally resistant substrates to ..

Synthesis and Characterization of Novel 2-Amino-3-benzoylthiophene Derivatives as Biased Allosteric Agonists and Modulators of the Adenosine A(1) Receptor

Celine Valant, Luigi Aurelio, Shane M Devine, Trent D Ashton, Jonathan M White, Patrick M Sexton, Arthur Christopoulos, Peter J Scammells

2012-03-08

A series of novel 2-amino-3-benzoylthiophenes (2A3BTs) were screened using a functional assay of A(1)R mediated phosphorylation of..

Copper complexes of a novel non-innocent quadridentate ligand

Gojko Buncic, Zhiguang Xiao, Simon C Drew, Jonathan M White, Anthony G Wedd, Paul S Donnelly

2012-01-01

Quadridentate ligand H(2)L binds Cu(I) to form salt [Cu(I)(H(2)L)]BF(4) which undergoes aerial oxidation in solution with isolatio..

Oxidative Damage of Pyrimidine Nucleosides by the Environmental Free Radical Oxidant NO3 center dot in the Absence and Presence of NO2 center dot and Other Radical and Non-Radical Oxidants

Catrin Goeschen, Jonathan M White, Robert W Gable, Uta Wille

2012-01-01

Analysis of the products formed in the reaction of the environmental free radical oxidant NO 3• with permethylated uridine 1 and t..

Synthesis and X-Ray Crystal Structure of Cynandione B Analogues

Lisa PT Hong, Jonathan M White, Christopher D Donner

2012-01-01

The synthesis of analogues of cynandione B, a phenolic acetophenone from Cynanchum taiwanianum, is described. The one-step convers..

The Synthesis of a Cubane-Substituted Dipeptide

Quentin I Churches, Roger J Mulder, Jonathan M White, John Tsanaktsidis, Peter J Duggan

2012-01-01

Amino acids and peptides bearing cyclic hydrocarbon side-chains are of interest in the development of a wide range of bioactive mo..

Structures of N,N-Dialkoxyamides: Pyramidal Anomeric Amides with Low Amidicity

Stephen A Glover, Jonathan M White, Adam A Rosser, Katherine M Digianantonio

2011-12-02

The first X-ray structures of two anomeric N,N-dialkoxyamides (2 and 3) have been obtained, which confirm that they are highly pyr..

1,3-Dipolar Cycloaddition-Decarboxylation Reactions of an Azomethine Ylide with Isatoic Anhydrides: Formation of Novel Benzodiazepinones

Asha M D'Souza, Nadia Spiccia, Jose Basutto, Pawel Jokisz, Leon S-M Wong, Adam G Meyer, Andrew B Holmes, Jonathan M White, John H Ryan

2011-02-04

A nonstabilized azomethine ylide reacts with a wide range of substituted isatoic anhydrides to afford novel 1,3-benzodiazepin-5-on..