Kava in the Treatment of Chronic Anxiety

S-adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: Efficacy and effects of histamine and carnitine as moderators of response

Jerome Sarris, George I Papakostas, Ottavio Vitolo, Maurizio Fava, David Mischoulon

2014-08-01

OBJECTIVE: To assess the antidepressant efficacy of S-adenosyl methionine (SAMe), a naturally occurring methyl donor, versus the s..

Naturopathic medicine for treating self-reported depression and anxiety: An observational pilot study of naturalistic practice

J Sarris, S Gadsden, I Schweitzer

2014-05-01

Overview: We conducted the first observational study of a case series of naturopathic consultations of adults who presented with s..

Integrative mental healthcare White Paper: Establishing a new paradigm through research, education, and clinical guidelines

J Sarris, R Glick, R Hoenders, J Duffy, J Lake

2014-01-01

Mental illness accounts for about one-third of adult disability globally, reflecting marked societal and personal suffering, and e..

The International Network of Integrative Mental Health (INIMH)

J Sarris, R Glick, C Helgason, C Veizer, J Lake

2014-01-01

To address the current challenges facing mental healthcare, the International Network of Integrative Mental Health (INIMH: www.INI..

Kava for the Treatment of Generalized Anxiety Disorder RCT: Analysis of Adverse Reactions, Liver Function, Addiction, and Sexual Effects

J Sarris, C Stough, R Teschke, ZT Wahid, CA Bousman, G Murray, KM Savage, P Mouatt, C Ng, I Schweitzer

2013-11-01

Presently, little is known about a number issues concerning kava (Piper methysticum), including (i) whether kava has any withdrawa..

Kava in the Treatment of Generalized Anxiety Disorder A Double-Blind, Randomized, Placebo-Controlled Study

Jerome Sarris, Con Stough, Chad A Bousman, Zahra T Wahid, Greg Murray, Rolf Teschke, Karen M Savage, Ashley Dowell, Chee Ng, Isaac Schweitzer

2013-10-01

Kava (Piper methysticum) is a plant-based medicine, which has been previously shown to reduce anxiety. To date, however, no placeb..

Pharmacogenetic polymorphisms and response to escitalopram and venlafaxine over 8 weeks in major depression

Chee Ng, Jerome Sarris, Ajeet Singh, Chad Bousman, Keith Byron, Lai Huat Peh, Deidre Joy Smith, Chay Hoon Tan, Isaac Schweitzer

2013-09-01

OBJECTIVE: The objective of this study is to investigate the influence of the 5-HTTLPR (serotonin transporter-linked promoter regi..

Lifestyle management of unipolar depression

M Berk, J Sarris, CE Coulson, FN Jacka

2013-05-01

OBJECTIVE: To be used in conjunction with 'Pharmacological management of unipolar depression' [Malhi et al. Acta Psychiatr Scand 2..

Plant-Based Medicines for Anxiety Disorders, Part 2: A Review of Clinical Studies with Supporting Preclinical Evidence

Jerome Sarris, Erica McIntyre, David A Camfield

2013-04-01

Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the tr..

Aripiprazole as augmentation therapy in bipolar patients with current minor or subsyndromal mood symptoms.

Isaac Schweitzer, Jerome Sarris, Virginia Tuckwell, Kay Maguire, Deidre Smith, Chee Ng

2013-01-01

BACKGROUND: This study aims to evaluate the effectiveness of aripiprazole augmentation of maintenance treatment for bipolar disord..

Does a Medicinal Dose of Kava Impair Driving? A Randomized, Placebo-Controlled, Double-Blind Study

J Sarris, E Laporte, A Scholey, R King, A Pipingas, I Schweitzer, C Stough

2013-01-01

OVERVIEW: Increasing concerns over the potentially impairing effects of prescriptive sedative drugs such as benzodiazepines on dri..

Plant-Based Medicines for Anxiety Disorders, Part 1 A Review of Preclinical Studies

Jerome Sarris, Erica McIntyre, David A Camfield

2013-01-01

Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the tr..

Participant experiences from chronic administration of a multivitamin versus placebo on subjective health and wellbeing: a double-blind qualitative analysis of a randomised controlled trial

Jerome Sarris, Katherine HM Cox, David A Camfield, Andrew Scholey, Con Stough, Erin Fogg, Marni Kras, David J White, Avni Sali, Andrew Pipingas

2012-12-14

BACKGROUND: While many randomised controlled trials have been conducted on multivitamins, to our knowledge no qualitative research..

St John's Wort (Hypericum perforatum) versus Sertraline and Placebo in Major Depressive Disorder: Continuation Data from a 26-Week RCT

J Sarris, M Fava, I Schweitzer, D Mischoulon

2012-11-01

Hypericum perforatum (St John's wort: SJW) has been extensively studied as an antidepressant in short-term trials, however little ..

The Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review of Randomized, Controlled Human Clinical Trials

Matthew P Pase, James Kean, Jerome Sarris, Chris Neale, Andrew B Scholey, Con Stough

2012-07-01

OBJECTIVES: Traditional knowledge suggests that Bacopa monnieri enhances cognitive performance. Such traditional beliefs have now ..

Complementary medicine, self-help, and lifestyle interventions for Obsessive Compulsive Disorder (OCD) and the OCD spectrum: A systematic review

Jerome Sarris, David Camfield, Michael Berk

2012-05-01

BACKGROUND: In Obsessive Compulsive Disorder (OCD) current standard pharmacotherapies may be of limited efficacy. Non-conventional..

'Omic' Genetic Technologies for Herbal Medicines in Psychiatry

Jerome Sarris, Chee Hong Ng, Isaac Schweitzer

2012-04-01

The field of genetics, which includes the use of 'omic' technologies, is an evolving area of science that has emerging application..

Complementary Medicine, Exercise, Meditation, Diet, and Lifestyle Modification for Anxiety Disorders: A Review of Current Evidence

J Sarris, S Moylan, DA Camfield, MP Pase, D Mischoulon, M Berk, FN Jacka, I Schweitzer

2012-01-01

Use of complementary medicines and therapies (CAM) and modification of lifestyle factors such as physical activity, exercise, and ..

INTEGRATIVE MENTAL HEALTH (IMH): PARADIGM, RESEARCH, AND CLINICAL PRACTICE

James Lake, Chanel Helgason, Jerome Sarris

2012-01-01

This paper provides an overview of the rapidly evolving paradigm of "Integrative Mental Health (IMH)." The paradigm of contemporar..

Herbal medicine for depression, anxiety and insomnia: A review of psychopharmacology and clinical evidence

Jerome Sarris, Alexander Panossian, Isaac Schweitzer, Con Stough, Andrew Scholey

2011-12-01

Research in the area of herbal psychopharmacology has increased markedly over the past decades. To date however, a comprehensive r..

Do long-chain n-3 fatty acids reduce arterial stiffness? A meta-analysis of randomised controlled trials

Matthew P Pase, Natalie A Grima, Jerome Sarris

2011-10-01

Fish oils, rich in long-chain n-3 PUFA, are known to reduce various risk factors for CVD. However, conclusive evidence regarding t..

Adjunctive nutraceuticals with standard pharmacotherapies in bipolar disorder: a systematic review of clinical trials

Jerome Sarris, David Mischoulon, Isaac Schweitzer

2011-08-01

OBJECTIVE:   Studies using augmentation of pharmacotherapies with nutraceuticals in bipolar disorder (BD) have been conducted and ..

Nutraceuticals in the treatment of Obsessive Compulsive Disorder (OCD): A review of mechanistic and clinical evidence

David A Camfield, Jerome Sarris, Michael Berk

2011-06-01

Obsessive-compulsive disorder (OCD) is a debilitating mental illness which has a significant impact on quality of life. First-line..

A systematic review of insomnia and complementary medicine

Jerome Sarris, Gerard J Byrne

2011-04-01

In concert with growing public interest in complementary and alternative medicine (CAM), these therapies and products have been in..

A Randomized, Controlled Trial of Meditation for Work Stress, Anxiety and Depressed Mood in Full-Time Workers

R Manocha, D Black, J Sarris, C Stough

2011-01-01

Objective. To assess the effect of meditation on work stress, anxiety and mood in full-time workers. Methods. 178 adult workers pa..

Kava: a comprehensive review of efficacy, safety, and psychopharmacology

Jerome Sarris, Emma LaPorte, Isaac Schweitzer

2011-01-01

OVERVIEW: Kava (Piper methysticum) is a South Pacific psychotropic plant medicine that has anxiolytic activity. This effect is ach..