Progressive Aphasia And Amyloid Deposition: A Multidisciplinary Approach To Improving Dementia Diagnosis

Grant number: 630489 | Funding period: 2010 - 2012

Completed

Abstract

We aim to understand the role of amyloid deposition in the genesis of symptoms in Alzheimer's disease. Patients presenting with progressive deterioration of language (aphasia) some of whom are known to have Alzheimer's disease will be studied using brain imaging techniques, including a PET method (PiB) that labels amyloid in vivo, and to compare imaging changes with a range of language assessments. This will improve the early diagnosis and management of patients with progressive aphasia.