THE ASSOCIATIONS BETWEEN COGNITIVE DECLINE AND GENETIC POLYMORPHISMS, HORMONES AND CARDIOVQSCULAR RISK FACTORS IN WOMEN

Influence of Physical Activity Levels and Functional Capacity on Brain beta-Amyloid Deposition in Older Women

Raquel Pedrero-Chamizo, Cassandra Szoeke, Lorraine Dennerstein, Stephen Campbell

2021-07-09

Physical activity (PA) and Alzheimer's disease are associated. However, how PA influences the cerebral β-amyloid (Aβ) burden remai..

Sex hormones, vascular factors and cognition

C Szoeke, SJ Downie, AF Parker, S Phillips

2021-06-21

After more than a century of research, we have failed to develop a pharmacological prevention or cure for dementia. There are stro..

Effect of a 24-month physical activity program on brain changes in older adults at risk of Alzheimer's disease: the AIBL active trial

Vijay K Venkatraman, Andrew Sanderson, Kay L Cox, Kathryn A Ellis, Christopher Steward, Pramit M Phal, Alexandra Gorelik, Matthew J Sharman, Victor L Villemagne, Michelle Lai, Elizabeth Cyarto, Bernd Merkel, David Ames, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Nicola T Lautenschlager, Patricia M Desmond

2020-05-01

White matter hyperintensities (WMHs) are a risk factor for cognitive decline. Physical activity (PA) is associated with lower WMH...

Mid-life predictors of late-life depressive symptoms; determining risk factors spanning two decades in the Women's Heathy Ageing Project.

Katherine E Campbell, Alexandra Gorelik, Cassandra E Szoeke, Lorraine Dennerstein

2020-01-01

BACKGROUND: Data available from longitudinal studies of adequate duration to explore midlife risk factors for late life higher dep..

Depression related cerebral pathology and its relationship with cognitive functioning: A systematic review

Alec Jamieson, Alicia M Goodwill, Mario Termine, Stephen Campbell, Cassandra Szoeke

2019-05-01

BACKGROUND: Depression's relationship with cerebral abnormalities and cognitive decline is temporally dynamic. Despite clear clini..

Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Catherine Owens Johnson, Nguyen Minh, Gregory A Roth, Emma Nichols, Tahiya Alam, Degu Abate, Foad Abd-Allah, Ahmed Abdelalim, Haftom Niguse Abraha, Niveen Me Abu-Rmeileh, Oladimeji M Adebayo, Abiodun Moshood Adeoye, Gina Agarwal, Sutapa Agrawal, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Fares Alahdab, Raghib Ali, Nelson Alvis-Guzman

2019-05-01

BACKGROUND: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke ca..

Robust Norms for Neuropsychological Tests of Verbal Episodic Memory in Australian Women

Alicia M Goodwill, Stephen Campbell, Victor W Henderson, Alexandra Gorelik, Lorraine Dennerstein, Michael McClung, Cassandra Szoeke

2019-05-01

OBJECTIVE: Robust norms for neuropsychological tests may offer superior clinical utility to conventional norms, in their ability t..

Diet and biomarkers of Alzheimer's disease: a systematic review and meta-analysis

Edward Hill, Alicia M Goodwill, Alexandra Gorelik, Cassandra Szoeke

2019-04-01

Alzheimer's disease (AD) risk increases with age and lacks efficacious pharmacological options. Summaries of the existing evidence..

Longitudinal nutritional changes in aging Australian women

Edward Hill, Allison Hodge, Peter Clifton, Nitin Shivappa, James R Hebert, Lorraine Dennerstein, Stephen Campbell, Cassandra Szoeke

2019-03-01

BACKGROUND AND OBJECTIVES: The importance of diet for the maintenance of health during aging is attracting a growing body of resea..

Apolipoprotein E4 Mediates the Association Between Midlife Dyslipidemia and Cerebral Amyloid in Aging Women

Cassandra Szoeke, Alicia M Goodwill, Alexandra Gorelik, Lorraine Dennerstein, Karen Caeyenberghs, Steven Simpson, Edward Hill, Stephen Campbell

2019-01-01

Cerebral amyloid-β (Aβ) plaques are the hallmark biomarker of Alzheimer's disease (AD) and are detectable decades before clinical ..

A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer's Disease: The AIBL Active-Study

Kay L Cox, Elizabeth Cyarto, Kathryn A Ellis, David Ames, Patricia Desmond, Pramit Phal, Matthew J Sharman, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Emily You, Sally Burrows, Michelle MY Lai, Nicola T Lautenschlager

2019-01-01

BACKGROUND: Previous studies have demonstrated that physical activity (PA) interventions can improve physical and cognitive outcom..

Self-reported confusion is related to global and regional beta-amyloid: data from the Women's healthy ageing project

Georgia E McCluskey, Paul Yates, Victor L Villemagne, Christopher Rowe, Cassandra EI Szoeke

2018-02-01

Disease-modifying treatments for Alzheimer's disease (AD) may require implementation during early stages of β-amyloid accumulation..

Adherence to the Mediterranean Diet Is not Related to Beta-Amyloid Deposition: Data from the Women's Healthy Ageing Project

E Hill, C Szoeke, L Dennerstein, S Campbell, P Clifton

2018-01-01

BACKGROUND: Research has indicated the neuroprotective potential of the Mediterranean diet. Adherence to the Mediterranean diet ha..

Dietary patterns and β-amyloid deposition in aging Australian women.

Edward Hill, Peter Clifton, Alicia M Goodwill, Lorraine Dennerstein, Stephen Campbell, Cassandra Szoeke

2018-01-01

INTRODUCTION: Evidence indicates that associations between diet and Alzheimer's disease may occur through biomarker pathways such ..

Vitamin D status is associated with executive function a decade later: Data from the Women's Healthy Ageing Project

Alicia M Goodwill, Stephen Campbell, Steven Simpson, Maria Bisignano, Cherie Chiang, Lorraine Dennerstein, Cassandra Szoeke

2018-01-01

OBJECTIVES: Vitamin D deficiency has been associated with cognitive decline and dementia in older adults. However, there is a pauc..

A Systematic Review and Meta-Analysis of The Effect of Low Vitamin D on Cognition

Alicia M Goodwill, Cassandra Szoeke

2017-10-01

BACKGROUND/OBJECTIVE: With an aging population and no cure for dementia on the horizon, risk factor modification prior to disease ..

Unhealthy habits persist: The ongoing presence of modifiable risk factors for disease in women (vol 12, e0173603, 2017)

Cassandra Szoeke, Christa Dang, Philippe Lehert, Martha Hickey, Meg E Morris, Lorraine Dennerstein, Stephen Campbell

2017-07-07

[This corrects the article DOI: 10.1371/journal.pone.0173603.].

Gender, marital status and longevity

Gemma Tatangelo, Marita McCabe, Stephen Campbell, Cassandra Szoeke

2017-06-01

Most studies report a positive relationship between marital status and health, with findings consistent across cultures and countr..

Unhealthy habits persist: The ongoing presence of modifiable risk factors for disease in women

Cassandra Szoeke, Christa Dang, Philippe Lehert, Martha Hickey, Meg E Morris, Lorraine Dennerstein, Stephen Campbell

2017-04-12

OBJECTIVES: Vascular disease remains a leading cause of death. There are several vascular risk factors identified that can mitigat..

Predictive Factors for Verbal Memory Performance Over Decades of Aging: Data from the Women's Healthy Ageing Project

Cassandra Szoeke, Philippe Lehert, Victor W Henderson, Lorraine Dennerstein, Patricia Desmond, Stephen Campbell

2016-10-01

BACKGROUND: Abnormalities in brain structure and function can occur several decades prior to the onset of cognitive decline. It is..

Cohort profile: Women's Healthy Ageing Project (WHAP) - a longitudinal prospective study of Australian women since 1990.

Cassandra Szoeke, Melissa Coulson, Stephen Campbell, Lorraine Dennerstein, null WHAP Investigators

2016-01-04

BACKGROUND: The cohort was commenced to examine women's health from midlife (45-55 years) before the menopausal transition and int..

Boomerang families and failure-to-launch: Commentary on adult children living at home

Katherine Burn, Cassandra Szoeke

2016-01-01

With a shifting economic climate and changes in social norms, young adults are increasingly reported to be living with their paren..

Prehypertension in midlife is associated with worse cognition a decade later in middle-aged and older women

Karren HM Chen, Victor W Henderson, Renerus J Stolwyk, Lorraine Dennerstein, Cassandra Szoeke

2015-05-01

BACKGROUND: previous studies raised the possibility that adverse health effects associated with elevated blood pressure (BP) begin..

The Women's Healthy Ageing Project: Fertile ground for investigation of healthy participants 'at risk' for dementia

Cassandra EI Szoeke, Joanne S Robertson, Christopher C Rowe, Paul Yates, Katherine Campbell, Colin L Masters, David Ames, Lorraine Dennerstein, Patricia Desmond

2013-12-01

Alzheimer's disease neuropathology (amyloid, tauopathies) and brain atrophy are present decades prior to manifestation of clinical..