Control of gene expression in a bacterial pathogen
Grant number: 1008055 | Funding period: 2011 - 2013
In this study we will characterise the manner in which genes essential for the virulence of Porphyromonas gingivalis, a bacterium associated with chronic periodontitis, are regulated. This will provide information on how this bacterium causes disease and may offer opportunities for the development of new treatment strategies.
Related publications (2)
The Porphyromonas gingivalis ferric uptake regulator orthologue does not regulate iron homeostasis
Catherine Butler, Helen Mitchell, Stuart Dashper, Eric Reynolds
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that has an absolute requirement for iron which it transports from..
The Porphyromonas gingivalis Ferric Uptake Regulator Orthologue Binds Hemin and Regulates Hemin-Responsive Biofilm Development
Catherine A Butler, Stuart G Dashper, Lianyi Zhang, Christine A Seers, Helen L Mitchell, Deanne V Catmull, Michelle D Glew, Jacqueline E Heath, Yan Tan, Hasnah SG Khan, Eric C Reynolds
Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingiv..