Stem Cell Targets For Lung Regeneration And Repair

Grant number: 1009374 | Funding period: 2011 - 2013

Completed

Abstract

The World Health Organisation estimates that by 2020, 12 of 68 million deaths worldwide will be attributed to lung disease with Chronic Obstructive Pulmonary Disease ranked the 3rd leading cause of death. Current therapies are palliative, providing symptomatic relief but no prospect of cure. In this project, we aim to determine how the ability of lung stem cells to repair the lung is compromised in disease in order to develop innovative therapies to arrest or reverse the disease process.