Understanding early changes in Multiple Sclerosis
Grant number: 1009757 | Funding period: 2011 - 2014
Multiple Sclerosis (MS) is caused by immune attack on the central nervous system (CNS), resulting in loss of the insulating material that surrounds nerve cells, as well as a degree of loss of the nerve cells themselves. Several partially effective therapies are available. A hurdle in developing CNS based therapies is methods to adequately test them. This study aims to assess biomarkers that could potentially be used to measure the damage in the optic nerve, a commonly affected structure in MS.
Related publications (4)
Early imaging predictors of longer term multiple sclerosis risk and severity in acute optic neuritis.
Sanuji Gajamange, Jim Stankovich, Gary Egan, Trevor Kilpatrick, Helmut Butzkueven, Joanne Fielding, Anneke van der Walt, Scott Kolbe
Background: Biomarkers are urgently required for predicting the likely progression of multiple sclerosis (MS) at the earliest stag..