Understanding What Causes Epilepsy

Grant number: 1009142 | Funding period: 2011 - 2013



About 100 000 people suffer from epilepsy in Australia with about one third poorly controlled with current anti-epileptic drugs. It is important to continue to develop novel modes of treatment for this debilitating disease. This project investigates an ion channel, known as HCN that is thought to be involved in making a brain epileptic. Understanding how changes in HCN channels make nerve cells and nerve networks more excitable will help us develop better strategies for designing drugs.