Understanding how herpes simplex virus hides in the nervous system

Grant number: 1005846 | Funding period: 2011 - 2013

Completed

Abstract

Herpes simplex virus causes cold sores and genital herpes. A person can only catch the virus once in their life, but it stays in their body and can cause occasional outbreaks of disease. This recurrent disease can be frequent and severe. The place where the herpes virus hides in a dormant state between outbreaks is in the nervous system. This project aims to learn more about how the virus becomes dormant and also whether the immune system is important in keeping the virus in this state.