The long-term consequences of toluene exposure on the maturing brain.

Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex

Alec LW Dick, Qiongyi Zhao, Rose Crossin, Danay Baker-Andresen, Xiang Li, Janette Edson, Simone Roeh, Victoria Marshall, Timothy W Bredy, Andrew J Lawrence, Jhodie R Duncan

2020-07-07

Inhalants containing the volatile solvent toluene are misused to induce euphoria or intoxication. Inhalant abuse is most common du..

Altered body weight associated with substance abuse: a look beyond food intake

Rose Crossin, Andrew J Lawrence, Zane B Andrews, Jhodie R Duncan

2019-01-01

Background: Substance abuse can cause a range of harmful secondary health consequences, including body weight changes. These remai..

The persistence of growth impairments associated with adolescent inhalant abuse following sustained abstinence

Rose Crossin, Sheree Cairney, Andrew John Lawrence, Jhodie Rubina Duncan

2018-01-01

Background: Abuse of inhalants containing the volatile solvent toluene is a significant public health issue, especially for adoles..

Adolescent inhalant abuse leads to other drug use and impaired growth; implications for diagnosis

Rose Crossin, Sheree Cairney, Andrew J Lawrence, Jhodie R Duncan

2017-02-01

OBJECTIVE: Abuse of inhalants containing the volatile solvent toluene is a significant public health issue, especially for adolesc..

Toluene inhalation in adolescent rats reduces flexible behaviour in adulthood and alters glutamatergic and GABAergic signalling

Teri M Furlong, Jhodie R Duncan, Laura H Corbit, Caroline D Rae, Benjamin D Rowlands, Anthony D Maher, Fatima A Nasrallah, Carol J Milligan, Steven Petrou, Andrew J Lawrence, Bernard W Balleine

2016-12-01

Toluene is a commonly abused inhalant that is easily accessible to adolescents. Despite the increasing incidence of use, our under..

Chronic intermittent toluene inhalation in adolescent rats results in metabolic dysfunction with altered glucose homeostasis

ALW Dick, A Simpson, A Qama, Z Andrews, AJ Lawrence, JR Duncan

2015-11-01

BACKGROUND AND PURPOSE: Abuse of toluene-containing inhalants is an increasing public health problem, especially among adolescents..

NMDA receptor binding is reduced within mesocorticolimbic regions following chronic inhalation of toluene in adolescent rats

Alec Lindsay Ward Dick, Tine Pooters, Sarah Gibbs, Emma Giles, Ashleigh Qama, Andrew John Lawrence, Jhodie Rubina Duncan

2015-10-22

The purposeful inhalation of volatile solvents, such as toluene, to induce self-intoxication is prevalent, particularly within ado..

Chronic intermittent toluene inhalation initiated during adolescence in rats does not alter voluntary consumption of ethanol in adulthood

Alec LW Dick, Andrew J Lawrence, Jhodie R Duncan

2014-09-01

Voluntary inhalation of organic solvents, such as toluene, is particularly prevalent in adolescent populations and is considered t..

Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats

Alec LW Dick, Martin Axelsson, Andrew J Lawrence, Jhodie R Duncan

2014-04-01

RATIONALE: Inhalant abuse is prevalent in adolescent populations, with chronic use resulting in neurobiological and cognitive abno..

Adolescent Toluene Inhalation in Rats Affects White Matter Maturation with the Potential for Recovery Following Abstinence

Jhodie Rubina Duncan, Alec Lindsay Ward Dick, Gary Egan, Scott Kolbe, Maria Gavrilescu, David Wright, Dan Ian Lubman, Andrew John Lawrence

2012-09-18

Inhalant misuse is common during adolescence, with ongoing chronic misuse associated with neurobiological and cognitive abnormalit..