Investigating The Molecular Basis Of T-Cell Receptor Cross-Reactivity

Grant number: DP110102078 | Funding period: 2011 - 2013

Completed

Abstract

This project will explore the basis of unexpected immune reactions whereby the immune system mistakes one molecular structure for another, a phenomenon known as cross-reactivity. This project will examine how often this is due to molecular mimicry, potentially explaining why immune T cells sometimes react inappropriately to different agents.