Are Alternative Histones Important Regulators of Transcription in Plasmodium Falciparum?

Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences

J Tang, SA Chisholm, LM Yeoh, PR Gilson, AT Papenfuss, KP Day, M Petter, MF Duffy

2020-12-01

Background: The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nu..

Activation and clustering of a Plasmodium falciparum var gene are affected by subtelomeric sequences

MF Duffy, J Tang, F Sumardy, HHT Nguyen, SA Selvarajah, GA Josling, KP Day, M Petter, GV Brown

2017-01-01

The Plasmodium falciparum var multigene family encodes the cytoadhesive, variant antigen PfEMP1. P. falciparum antigenic variation..

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

GA Josling, M Petter, SC Oehring, AP Gupta, O Dietz, DW Wilson, T Schubert, G Längst, PR Gilson, BS Crabb, S Moes, P Jenoe, SW Lim, GV Brown, Z Bozdech, TS Voss, MF Duffy

2015-06-10

Summary During red-blood-cell-stage infection of Plasmodium falciparum, the parasite undergoes repeated rounds of replication, egr..

H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum

M Petter, SA Selvarajah, CC Lee, WH Chin, AP Gupta, Z Bozdech, GV Brown, MF Duffy

2013-03-01

Summary: Histone variants are important components of eukaryotic chromatin and can alter chromatin structure to confer specialized..