Are alternative histones important regulators of transcription in Plasmodium falciparum?
Grant number: DP110100483 | Funding period: 2011 - 2014
Malaria parasites depend on tightly controlled expression of their genes for maintaining infection and causing disease. The project will identify mechanisms of gene control used by parasites; these mechanisms may provide targets for malaria therapies.
Related publications (3)
Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences
Jingyi Tang, Scott A Chisholm, Lee M Yeoh, Paul R Gilson, Anthony T Papenfuss, Karen P Day, Michaela Petter, Michael F Duffy
BACKGROUND: The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nu..
A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression
Gabrielle A Josling, Michaela Petter, Sophie C Oehring, Archna P Gupta, Olivier Dietz, Danny W Wilson, Thomas Schubert, Gernot Laengst, Paul R Gilson, Brendan S Crabb, Suzette Moes, Paul Jenoe, Shu Wei Lim, Graham V Brown, Zbynek Bozdech, Till S Voss, Michael F Duffy